SCHEMBL5863653

SCHEMBL5863653

CN(C)c1cccc2c(S(=O)(=O)NC(Cc3c[nH]c4ccccc34)C(=O)O)cccc12

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.64
MMP9 P14780 12/20 0.62
MMP2 P08253 10/20 0.62
KMT2A Q03164 1/20 0.59
KCNA5 P22460 1/20 0.56
ADAM17 P78536 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4133797 1.00 SMN1; SMN2 (0.64) SMN1; SMN2MMP9MMP2KMT2AKCNA5
Cyclohexylamine SCHEMBL6813877 0.91 SMN1; SMN2 (0.55) SMN1; SMN2MMP9MMP2KMT2AADAM17
Cyclohexylamine SCHEMBL6813880 0.91 SMN1; SMN2 (0.55) SMN1; SMN2MMP9MMP2KMT2AADAM17
SCHEMBL5399341 0.90 SMN1; SMN2 (0.53) SMN1; SMN2MMP9MMP2KMT2AKCNA5
SCHEMBL10412558 0.87 ACE (0.52) SMN1; SMN2MMP9MMP2KMT2A
SCHEMBL3257069 0.87 NR3C1 (0.69)
SCHEMBL29776944 0.86 SMN1; SMN2 (0.70) SMN1; SMN2MMP9MMP2KMT2AKCNA5
SCHEMBL20335103 0.86 SMN1; SMN2 (0.70) SMN1; SMN2MMP9MMP2KMT2AKCNA5
SCHEMBL20335105 0.86 SMN1; SMN2 (0.70) SMN1; SMN2MMP9MMP2KMT2AKCNA5
SCHEMBL7299191 0.86 SMN1; SMN2 (0.70) SMN1; SMN2MMP9MMP2KMT2AKCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119174932-A Preparation method of capillary chromatographic column based on metal organic framework material and used for chiral separation 上海大学 2024-12-24 CN disclosed
EP-0748247-B1 Macrocyclic antibiotics as separation agents UNIV MISSOURI (US) 2012-06-20 EP disclosed
US-7008533-B2 Macrocyclic antibiotics as separation agents CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2006-03-07 US disclosed
US-20050243305-A1 Tamper-resistant authentication mark for use in product or product packaging authentication VIG RAKESH 2005-11-03 US disclosed
EP-1549502-A1 AUTHENTICATION MARK FOR A PRODUCT OR PRODUCT PACKAGE Sun Chemical B.V. (NL) 2005-07-06 EP disclosed
EP-1532578-A1 TAMPER-RESISTANT AUTHENTICATION MARK FOR USE IN PRODUCT OR PRODUCT PACKAGING AUTHENTICATION Verification Technologies, Inc. (US) 2005-05-25 EP disclosed
CN-1575494-A Product packaging including digital data VERIFICATION TECHNOLOGIES INC (US) 2005-02-02 CN disclosed
WO-2004033228-A1 AUTHENTICATION MARK FOR A PRODUCT OR PRODUCT PACKAGE SUN CHEMICAL B.V. (NL) 2004-04-22 WO disclosed
WO-2004013805-A1 TAMPER-RESISTANT AUTHENTICATION MARK FOR USE IN PRODUCT OR PRODUCT PACKAGING AUTHENTICATION VERIFICATION TECHNOLOGIES, INC. D/B/A VERITEC (US) 2004-02-12 WO disclosed
US-6669842-B1 Crystallization, precipitation, filtration, electrophoresis, and chromatography using ansamacrolides, macrolides, macrocyclic peptides, or polyenes; resolution CURATORS OF THE UNIVERSITY OF MISSOURI 2003-12-30 US disclosed
EP-0748247-A4 MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS UNIV MISSOURI (US) 1998-05-06 EP disclosed
US-5629424-A Stereoselective adsorptive bubble process THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1997-05-13 US disclosed
US-5626757-A RESOLUTION OF ENANTIOMORPHS BY ELECTROPHORESIS AND CHROMATOGRAPHY ADVANCED SEPARATION TECHNOLOGIES INC. (US) 1997-05-06 US disclosed
EP-0748247-A1 MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1996-12-18 EP disclosed
WO-1995022390-A1 MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1995-08-24 WO disclosed