Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.44 |
| ▸ | FABP7 | O15540 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30889906 | 0.86 | KMT2A (0.45) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL30272536 | 0.86 | KMT2A (0.45) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL15939517 | 0.86 | KMT2A (0.45) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL755810 | 0.81 | KMT2A (0.45) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL29362617 | 0.80 | KMT2A (0.59) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL113270 | 0.80 | KMT2A (0.59) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL30042128 | 0.80 | KMT2A (0.59) | KMT2AFABP5FABP7CA1CA2 | |
| Acetone SCHEMBL7446589 | 0.79 | KMT2A (0.55) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL28457176 | 0.79 | KMT2A (0.39) | KMT2AFABP5FABP7CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL16430851 | 0.79 | KMT2A (0.57) | KMT2AFABP5FABP7CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030118-B2 | Pyrrolotriazinone compounds and their use to treat diseases | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-04-18 | — | — | US | disclosed |