Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.50 |
| ▸ | FABP7 | O15540 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30042128 | 0.95 | KMT2A (0.59) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL29362617 | 0.95 | KMT2A (0.59) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL113270 | 0.95 | KMT2A (0.59) | KMT2AFABP5FABP7CA1CA2 | |
| Hydrochloric Acid SCHEMBL1234617 | 0.93 | KMT2A (0.57) | KMT2AFABP5FABP7CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL16430851 | 0.93 | KMT2A (0.57) | KMT2AFABP5FABP7CA1CA2 | |
| Urethane SCHEMBL20239060 | 0.90 | KMT2A (0.52) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL14862502 | 0.86 | KMT2A (0.49) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL29608029 | 0.84 | KMT2A (0.55) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL410205 | 0.84 | KMT2A (0.55) | KMT2AFABP5FABP7CA1CA2 | |
| Succinimide SCHEMBL5070373 | 0.82 | TSHR (0.49) | KMT2AFABP5FABP7CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140897-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1140897-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039115-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |