⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560631 | 0.85 | — | — | |
| SCHEMBL571858 | 0.79 | ALDH1A1 (0.30) | — | |
| SCHEMBL9591104 | 0.79 | ALDH1A1 (0.30) | — | |
| Methyl Alcohol SCHEMBL9799142 | 0.77 | — | — | |
| SCHEMBL19768683 | 0.76 | — | — | |
| SCHEMBL938172 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL1404 | 0.75 | — | — | |
| SCHEMBL2154133 | 0.75 | TSHR (0.38) | — | |
| SCHEMBL50101 | 0.75 | TSHR (0.38) | — | |
| SCHEMBL1810 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750778-A | FLUOROALKANOIC ACIDS AND DERIVATIVES | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | claimed |
| EP-0468681-B1 | Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | claimed |
| EP-0468681-A1 | Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | claimed |
| EP-3760623-B1 | TETRAHYDRO-PYRIDO[3,4-B]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2026-03-18 | — | — | EP | disclosed |
| EP-4638436-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-10-29 | — | — | EP | disclosed |
| US-20250114338-A1 | TETRAHYDRO-PYRIDO[3,4-b]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | GENENTECH, INC. (US) | 2025-04-10 | — | — | US | disclosed |
| US-12233052-B2 | Tetrahydro-pyrido[3,4-b]indole estrogen receptor modulators and uses thereof | GENENTECH, INC. (US) | 2025-02-25 | — | — | US | disclosed |
| US-20240254118-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. | 2024-08-01 | — | — | US | disclosed |
| WO-2024137852-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| CN-118005631-A | Tetrahydro-pyrido [3,4-b ] indole estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117865872-A | Tetrahydro-pyrido [3,4-b ] indole estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-0468681-B1 | Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | disclosed |
| EP-0647217-A1 | 4-ACYLAMINOBENZAMIDES AND THEIR USE AS FUNGICIDES. | ZENECA LTD (GB) | 1995-04-12 | — | — | EP | disclosed |
| CN-1090269-A | Mycocide | ZENECA LTD (GB) | 1994-08-03 | — | — | CN | disclosed |
| WO-1994000422-A2 | 4-ACYLAMINOBENZAMIDES AND THEIR USE AS FUNGICIDES | ZENECA LIMITED (GB) | 1994-01-06 | — | — | WO | disclosed |
| EP-0468681-A1 | Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |
| EP-0468681-A1 | Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |
| EP-0468683-A1 | Fungicidal acylamidobenzamides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |
| US-4749414-A | CONTAINERS FOR INTEGRAL FLUID DELIVERY | THE DOW CHEMICAL COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
| US-4664978-A | ADHERENT LAYER OF FLUORINE-CONTAINING CELLULOSE ETHER ESTER | THE DOW CHEMICAL COMPANY (US) | 1987-05-12 | — | — | US | disclosed |