Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205129 | 0.95 | PTGS2 (0.62) | PTGS2PTGS1PDPK1CA1CA2 | |
| SCHEMBL5865525 | 0.87 | PTGS2 (0.65) | PTGS2PTGS1PDPK1CA1CA2 | |
| SCHEMBL5204981 | 0.86 | PTGS2 (0.65) | PTGS2PTGS1PDPK1CA1CA2 | |
| SCHEMBL5204127 | 0.86 | PTGS2 (0.70) | PTGS2PTGS1PDPK1CA1CA2 | |
| SCHEMBL5865454 | 0.85 | PTGS2 (0.62) | PTGS2PTGS1 | |
| Dimethylamine SCHEMBL5205078 | 0.84 | PTGS2 (0.45) | PTGS2PTGS1PDPK1 | |
| SCHEMBL5204716 | 0.84 | PTGS2 (0.62) | PTGS2PTGS1PDPK1CA1CA2 | |
| SCHEMBL5203083 | 0.84 | PTGS2 (0.62) | PTGS2PTGS1PDPK1CA1CA2 | |
| SCHEMBL5235013 | 0.84 | PTGS2 (0.62) | PTGS2PTGS1PDPK1CA1CA2 | |
| SCHEMBL5207563 | 0.84 | PTGS2 (0.62) | PTGS2PTGS1PDPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019144-B2 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP. (KR) | 2006-03-28 | — | — | US | disclosed |
| US-20050075507-A1 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CHEILJEDANG CORPORATION (KR) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075507-A1 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CYP4B1, CYP3A5, CYP7A1 | PTGS2 1769/4885PTGS1 523/4885PDPK1 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.