Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205583 | 0.92 | PTGS1 (0.46) | PTGS2PTGS1CA1CA2CHRNA7 | |
| SCHEMBL5203115 | 0.92 | PTGS2 (0.44) | PTGS2PTGS1CA1CA2CHRNA7 | |
| SCHEMBL5201449 | 0.89 | PTGS2 (0.52) | PTGS2 | |
| SCHEMBL5205173 | 0.88 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL5205172 | 0.88 | PTGS2 (0.49) | PTGS2PTGS1CA1CA2CHRNA7 | |
| SCHEMBL5202554 | 0.87 | CHRNA7 (0.44) | PTGS2PTGS1CA1CA2CHRNA7 | |
| SCHEMBL5201651 | 0.87 | PTGS2 (0.51) | PTGS2PTGS1CA1CA2KIF11 | |
| SCHEMBL5239915 | 0.87 | PTGS2 (0.50) | PTGS2PTGS1CA1CA2CHRNA7 | |
| SCHEMBL5205534 | 0.87 | PTGS2 (0.44) | PTGS2PTGS1CA1CA2CHRNA7 | |
| SCHEMBL5207586 | 0.87 | PTGS2 (0.47) | PTGS2PTGS1CA1CA2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019144-B2 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP. (KR) | 2006-03-28 | — | — | US | disclosed |
| US-20050075507-A1 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CHEILJEDANG CORPORATION (KR) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075507-A1 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CYP4B1, CYP3A5, CYP7A1 | PTGS2 1769/4885PTGS1 523/4885CA1 1852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.