Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL28234426 | 0.94 | POLB (0.50) | POLBNPSR1NR1I2KCNH2MEN1 | |
| Biphenyl SCHEMBL14829854 | 0.79 | MEN1 (0.56) | MEN1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL29176889 | 0.79 | NR1I2 (0.50) | POLBNPSR1NR1I2KCNH2MEN1 | |
| Catechol SCHEMBL466512 | 0.79 | POLB (0.46) | POLBNPSR1NR1I2KCNH2MEN1 | |
| SCHEMBL9505701 | 0.78 | POLB (0.46) | POLBNPSR1NR1I2KCNH2MEN1 | |
| Phenyl Dihydrogen Phosphate SCHEMBL10380848 | 0.78 | SRC (0.70) | POLBNPSR1NR1I2KCNH2ALDH1A1 | |
| Biphenyl SCHEMBL28166821 | 0.76 | LPAR3 (0.58) | — | |
| Biphenyl SCHEMBL5419355 | 0.75 | LPAR3 (0.67) | TSHR | |
| SCHEMBL915623 | 0.75 | ACP3 (0.45) | POLBNPSR1NR1I2KCNH2TSHR | |
| Biphenyl SCHEMBL924817 | 0.75 | ALDH1A1 (0.54) | POLBNPSR1NR1I2KCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037691-B2 | Kinase mimic catalysts for asymmetric synthesis of phosphorylated inositols and cycloalkanols | THE TRUSTEES OF BOSTON COLLEGE (US) | 2006-05-02 | — | — | US | disclosed |
| US-20050267291-A1 | Kinase mimic catalysts for asymmetric synthesis of phosphorylated inositols and cycloalkanols | THE TRUSTEES OF BOSTON COLLEGE | 2005-12-01 | — | — | US | disclosed |
| US-20030100090-A1 | Kinase mimic catalysts for asymmetric synthesis of phosphorylated insitols and cycloalkanols | THE TRUSTEES OF BOSTON COLLEGE | 2003-05-29 | — | — | US | disclosed |
| WO-2003004141-A2 | KINASE MIMIC CATALYSTS FOR ASYMMETRIC SYNTHESIS OF PHOSPHORYLATED INSITOLS AND CYCLOALKANOLS | THE TRUSTEES OF BOSTON COLLEGE (US) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267291-A1 | Kinase mimic catalysts for asymmetric synthesis of phosphorylated inositols and cycloalkanols | IPMK, DMPK, IP6K1 | POLB 1341/4885NPSR1 2564/4885NR1I2 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.