Urethane

Urethane

SCHEMBL5865873

CCOC(N)=O.O=C=N[N+](=O)[O-]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.54
LMNA P02545 3/20 0.34
GLA P06280 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.31
HSD17B10 Q99714 2/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL4443807 0.81 ALOX15 (0.68) ALOX15LMNAALDH1A1HSD17B10MGAM
Urethane SCHEMBL7922234 0.79 ALOX15 (0.65) ALOX15LMNAALDH1A1HSD17B10MGAM
Urethane SCHEMBL14862846 0.78 ALOX15 (0.71) ALOX15LMNAGLANPC1ALDH1A1
Urethane SCHEMBL28243396 0.78 ALOX15 (0.71) ALOX15LMNAGLANPC1ALDH1A1
Urethane SCHEMBL6233111 0.76
Urethane SCHEMBL1177244 0.76
Urethane SCHEMBL10632237 0.75 ALOX15 (0.65) ALOX15LMNAALDH1A1HSD17B10MGAM
Urethane SCHEMBL8516315 0.74
Urethane SCHEMBL10338136 0.73 ALOX15 (0.62) ALOX15LMNAALDH1A1HSD17B10MGAM
Urethane SCHEMBL8505249 0.73 ALOX15 (1.00) ALOX15LMNAALDH1A1HSD17B10MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7119131-B2 Urethane binder compositions for foundry applications DOW GLOBAL TECHNOLOGIES, INC. (US) 2006-10-10 US claimed
WO-2004096731-A2 URETHANE BINDER COMPOSITIONS FOR FOUNDRY APPLICATIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2004-11-11 WO claimed
US-20040214917-A1 Urethane binder compositions for foundry applications ANGUS CHEMICAL COMPANY 2004-10-28 US claimed