Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 13/20 | 0.49 |
| ▸ | TACR1 | P25103 | 13/20 | 0.49 |
| ▸ | TACR3 | P29371 | 13/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866414 | 0.87 | TACR2 (0.61) | TACR2TACR1TACR3MCHR1 | |
| SCHEMBL5866423 | 0.84 | TACR2 (0.61) | TACR2 | |
| SCHEMBL5866420 | 0.83 | TACR2 (0.48) | TACR2TACR1TACR3TSHRMCHR1 | |
| Citric Acid SCHEMBL7048901 | 0.79 | TACR2 (0.56) | TACR2 | |
| Citric Acid SCHEMBL5866413 | 0.79 | TACR2 (0.56) | TACR2 | |
| Citric Acid SCHEMBL5866407 | 0.78 | TACR2 (0.43) | TACR2TACR1TACR3TSHRMCHR1 | |
| SCHEMBL5866429 | 0.74 | HPGD (0.51) | TSHRHPGD | |
| SCHEMBL5866432 | 0.71 | CA1 (0.51) | TSHRHPGD | |
| Citric Acid SCHEMBL7044834 | 0.70 | TACR2 (0.58) | TACR2TACR1TACR3 | |
| SCHEMBL1387915 | 0.70 | TACR2 (0.70) | TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053213-B2 | Therapeutic heterocycles | ASTRAZENECA AB (SE) | 2006-05-30 | — | — | US | claimed |