Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 16/20 | 0.61 |
| ▸ | TACR1 | P25103 | 16/20 | 0.61 |
| ▸ | TACR3 | P29371 | 16/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866449 | 0.87 | TACR2 (0.49) | TACR2TACR1TACR3MCHR1 | |
| Citric Acid SCHEMBL7044834 | 0.76 | TACR2 (0.58) | TACR2TACR1TACR3 | |
| SCHEMBL5866420 | 0.75 | TACR2 (0.48) | TACR2TACR1TACR3MCHR1 | |
| SCHEMBL5866423 | 0.73 | TACR2 (0.61) | TACR2 | |
| SCHEMBL8314527 | 0.72 | HDAC1 (0.45) | TACR2MCHR1 | |
| Citric Acid SCHEMBL5866407 | 0.71 | TACR2 (0.43) | TACR2TACR1TACR3MCHR1 | |
| SCHEMBL1387917 | 0.70 | TACR2 (0.70) | TACR2 | |
| SCHEMBL1387915 | 0.70 | TACR2 (0.70) | TACR2 | |
| SCHEMBL6959139 | 0.70 | CCR5 (0.57) | TACR2TACR1TACR3 | |
| SCHEMBL6963702 | 0.69 | CCR5 (0.50) | TACR2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053213-B2 | Therapeutic heterocycles | ASTRAZENECA AB (SE) | 2006-05-30 | — | — | US | claimed |
| US-7053213-B2 | Therapeutic heterocycles | ASTRAZENECA AB (SE) | 2006-05-30 | — | — | US | disclosed |
| EP-0714392-B1 | HETEROCYCLES USEFUL AS NEUROKININ ANTAGONISTS | ZENECA LTD (GB) | 1998-11-04 | — | — | EP | disclosed |