Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20325546 | 0.80 | HDAC1 (0.47) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| SCHEMBL27083872 | 0.79 | HDAC1 (0.51) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| SCHEMBL15712764 | 0.79 | PKM (0.48) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| Hydrochloric Acid SCHEMBL27204419 | 0.76 | HTR2A (0.46) | KCNH2MCHR1MERTKCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL27165375 | 0.76 | HTR2A (0.46) | KCNH2MCHR1MERTKCHRNB2CHRNA4 | |
| SCHEMBL3537839 | 0.74 | DDB1 (0.41) | KCNH2MCHR1MERTKPIK3CDABL1 | |
| SCHEMBL31251090 | 0.74 | HDAC2 (0.44) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| Hydrochloric Acid SCHEMBL27165372 | 0.73 | HTR2A (0.50) | KCNH2MCHR1MERTKKDRCHRNB2 | |
| Hydrochloric Acid SCHEMBL27165645 | 0.73 | HTR2A (0.50) | KCNH2MCHR1MERTKKDRCHRNB2 | |
| SCHEMBL13970470 | 0.71 | MCHR1 (0.64) | KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |