Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 16/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866809 | 1.00 | ABL1 (0.51) | ABL1FGFR1KDRPDGFRAFGFR2 | |
| SCHEMBL5866631 | 1.00 | ABL1 (0.51) | ABL1FGFR1KDRPDGFRAFGFR2 | |
| SCHEMBL5866643 | 1.00 | ABL1 (0.51) | ABL1FGFR1KDRPDGFRAFGFR2 | |
| SCHEMBL5866636 | 1.00 | ABL1 (0.51) | ABL1FGFR1KDRPDGFRAFGFR2 | |
| SCHEMBL6582455 | 0.93 | ABL1 (0.53) | ABL1FGFR1KDRFLT1 | |
| SCHEMBL3539306 | 0.90 | ABL1 (0.52) | ABL1FGFR1KDRFLT1 | |
| SCHEMBL3533004 | 0.90 | ABL1 (0.52) | ABL1FGFR1KDRFLT1 | |
| SCHEMBL3534766 | 0.90 | ABL1 (0.52) | ABL1FGFR1KDRFLT1 | |
| SCHEMBL3533006 | 0.90 | ABL1 (0.52) | ABL1FGFR1KDRFLT1 | |
| SCHEMBL3541753 | 0.90 | ABL1 (0.52) | ABL1FGFR1KDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |