Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 6/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.38 |
| ▸ | FLT1 | P17948 | 4/20 | 0.38 |
| ▸ | FLT3 | P36888 | 6/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | BCR | P11274 | 2/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3532552 | 0.92 | PDPK1 (0.40) | PDPK1FGFR1FLT1FLT3ABL1 | |
| SCHEMBL5866757 | 0.90 | FGFR1 (0.48) | PDPK1FGFR1FLT1FLT3ABL1 | |
| SCHEMBL5866797 | 0.87 | PDPK1 (0.51) | PDPK1FGFR1FLT1FLT3ABL1 | |
| SCHEMBL5866785 | 0.87 | PDPK1 (0.44) | PDPK1FGFR1FLT1FLT3ABL1 | |
| SCHEMBL3536048 | 0.86 | PDPK1 (0.38) | PDPK1FGFR1FLT1FLT3ABL1 | |
| SCHEMBL3538825 | 0.86 | FOXO1 (0.39) | PDPK1FGFR1FLT1FLT3ABL1 | |
| SCHEMBL3535987 | 0.86 | MAPT (0.38) | PDPK1FGFR1FLT1FLT3ABL1 | |
| SCHEMBL5866691 | 0.84 | FGFR1 (0.40) | PDPK1FGFR1FLT1FLT3ABL1 | |
| SCHEMBL3539088 | 0.83 | FGFR1 (0.39) | PDPK1FGFR1FLT1FLT3ABL1 | |
| SCHEMBL3538875 | 0.82 | PDPK1 (0.49) | PDPK1FGFR1FLT1FLT3ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |