Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 11/20 | 0.40 |
| ▸ | FLT1 | P17948 | 10/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 7/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3534254 | 0.92 | FGFR1 (0.43) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL5866756 | 0.90 | FGFR1 (0.35) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL3540770 | 0.87 | FGFR1 (0.40) | FGFR1FLT1PDPK1ABL1 | |
| SCHEMBL5866778 | 0.86 | ABL1 (0.43) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL5866706 | 0.86 | FGFR1 (0.39) | FGFR1FLT1ABL1FLT3BCR | |
| SCHEMBL3538199 | 0.85 | FGFR1 (0.42) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL3536935 | 0.85 | FGFR1 (0.39) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL3536592 | 0.83 | FGFR1 (0.40) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL5866896 | 0.83 | FGFR1 (0.39) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL3595759 | 0.82 | FGFR1 (0.38) | FGFR1FLT1PDPK1ABL1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |