Guanidine

Guanidine

SCHEMBL5867103

N#CS.N=C(N)N.N=C(N)NN=C=S

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiocyanic Acid SCHEMBL28694942 0.98
Acetonitrile SCHEMBL28825390 0.85
SCHEMBL5072658 0.84
SCHEMBL28436707 0.84
Hydrochloric Acid SCHEMBL15994074 0.82
Hydrochloric Acid SCHEMBL197403 0.82
Iodide SCHEMBL20603123 0.82
Hydrochloric Acid SCHEMBL7112379 0.82
Hydrochloric Acid SCHEMBL342565 0.82
Iodide SCHEMBL28453451 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7074916-B2 Process for the separation of double-stranded/single-stranded nucleic acid structures QIAGEN GMBH (DE) 2006-07-11 US claimed
US-6180778-B1 SUCH AS DNA AND RNA, BY SELECTIVELY ABSORBING DOUBLE-STRANDED OR SINGLE-STRANDED NUCLEIC ACID OF A LIQUID SAMPLE TO A MINERAL SUPPORT, APPLYING TO SECOND SUPPORT THE OTHER OF THE NUCLEIC ACIDS IN AQUEOUS SOLUTION CONTAINING ALCOHOLS QIAGEN GMBH (DE) 2001-01-30 US claimed