SCHEMBL5867356

SCHEMBL5867356

CC(c1cn[nH]c1)c1cn(CC(=O)N(C)Cc2ccc(-c3ccc(F)cc3)cc2)c(SCc2ccc(F)cc2)nc1=O

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4411626 0.96 PLA2G7 (0.64) PLA2G7
SCHEMBL4415703 0.96 PLA2G7 (0.64) PLA2G7
SCHEMBL4415554 0.95 PLA2G7 (0.65) PLA2G7
SCHEMBL4425722 0.93 PLA2G7 (0.57) PLA2G7
SCHEMBL4414401 0.93 PLA2G7 (0.55) PLA2G7
SCHEMBL4416171 0.93 PLA2G7 (0.58) PLA2G7
SCHEMBL4425606 0.91 PLA2G7 (0.64) PLA2G7
SCHEMBL4426115 0.91 PLA2G7 (0.52) PLA2G7
SCHEMBL4425956 0.89 PLA2G7 (0.58) PLA2G7
SCHEMBL4412428 0.89 PLA2G7 (0.56) PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7115616-B2 Pyrimidinone compounds SMITHKLINE BEECHAM PLC (GB) 2006-10-03 US disclosed