SCHEMBL5867434

SCHEMBL5867434

CCCCC(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 6/20 0.58
KDM4E B2RXH2 1/20 0.55
MAPT P10636 1/20 0.55
THRB P10828 1/20 0.55
ALOX15 P16050 1/20 0.55
NFKB1 P19838 1/20 0.55
PTGS2 P35354 1/20 0.55
THPO P40225 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
ACE P12821 1/20 0.50
FOLH1 Q04609 1/20 0.47
FAAH O00519 4/20 0.47
MEN1 O00255 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.47
SLC6A5 Q9Y345 1/20 0.47
FNTA P49354 4/20 0.46
FNTB P49356 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5867431 1.00 NOD1 (0.58) NOD1KDM4EMAPTTHRBALOX15
SCHEMBL2356288 0.95 NOD1 (0.66) NOD1KDM4EMAPTTHRBALOX15
SCHEMBL2356282 0.95 NOD1 (0.66) NOD1KDM4EMAPTTHRBALOX15
SCHEMBL16190310 0.93 NOD1 (0.69) NOD1KDM4EMAPTTHRBALOX15
SCHEMBL2349133 0.93 NOD1 (0.69) NOD1KDM4EMAPTTHRBALOX15
SCHEMBL25187792 0.93 NOD1 (0.69) NOD1KDM4EMAPTTHRBALOX15
SCHEMBL2353176 0.93 NOD1 (0.69) NOD1KDM4EMAPTTHRBALOX15
SCHEMBL2355126 0.93 NOD1 (0.69) NOD1KDM4EMAPTTHRBALOX15
SCHEMBL21291889 0.93 NOD1 (0.69) NOD1KDM4EMAPTTHRBALOX15
SCHEMBL2355124 0.93 NOD1 (0.69) NOD1KDM4EMAPTTHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379214-A1 HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING SAME L'OREAL, S.A. (FR) 2004-01-14 EP claimed
US-20020159962-A1 Hair relaxer compositions comprising at least one hydroxide compound and at least one activating agent, and methods of using the same L'OREAL S.A. (FR) 2002-10-31 US claimed
WO-2002067875-A1 HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING THE SAME L'OREAL S.A. (FR) 2002-09-06 WO claimed
WO-2024205472-A1 COMPOSITION FOR USE IN PREVENTION AND/OR TREATMENT OF HUMAN TRANSTHYRETIN AMYLOIDOSIS OLOFSSON ANDERS (SE) 2024-10-03 WO disclosed
CN-118255830-A S1PR2 modulators and uses thereof 北京昌平实验室 2024-06-28 CN disclosed
WO-2018017408-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO disclosed
WO-2018017390-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO disclosed
US-7118736-B2 Hair relaxer compositions comprising at least one hydroxide compound and at least one activating agent, and methods of using the same L'OREAL (FR) 2006-10-10 US disclosed
EP-1379214-A1 HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING SAME L'OREAL, S.A. (FR) 2004-01-14 EP disclosed
US-20020159962-A1 Hair relaxer compositions comprising at least one hydroxide compound and at least one activating agent, and methods of using the same L'OREAL S.A. (FR) 2002-10-31 US disclosed
WO-2002067875-A1 HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING THE SAME L'OREAL S.A. (FR) 2002-09-06 WO disclosed
US-5889050-A IMMUNOMODULATOR ASTRA AKTIEBOLAG (SE) 1999-03-30 US disclosed
EP-0463514-B1 3.3'-Dithiobis (propionic acids) and esters thereof ASTRA AB (SE) 1995-04-05 EP disclosed
EP-0463514-A1 3.3'-Dithiobis (propionic acids) and esters thereof Astra Aktiebolag (SE) 1992-01-02 EP disclosed
US-4992267-A Mixture of alkali metal hydroxide and disulfide reducing agent JOHNSON PRODUCTS CO., INC. (US) 1991-02-12 US disclosed