Tert-Butanol

Tert-Butanol

SCHEMBL5867448

CC(C)(C)O.CCO.[LiH]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Tert-Butanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butanol SCHEMBL474820 0.95
Tert-Butanol SCHEMBL11063002 0.91
Tert-Butanol SCHEMBL11259725 0.91 TSHR (0.55)
Alcohol SCHEMBL595983 0.82 TSHR (0.55)
Alcohol SCHEMBL15880913 0.82 TSHR (0.55)
Tert-Butanol SCHEMBL5867069 0.81 TSHR (0.43)
Tert-Butanol SCHEMBL10441371 0.81 ALDH1A1 (0.43)
Tert-Butanol SCHEMBL27940828 0.80
Alcohol SCHEMBL27658536 0.80
Tert-Butanol SCHEMBL571470 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6986955-B2 Electronic and optical materials NGIMAT CO. (US) 2006-01-17 US disclosed