Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PANK1 | Q8TE04 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5868125 | 0.86 | MEN1 (0.41) | MEN1KMT2ACCR3F10NPSR1 | |
| SCHEMBL5868038 | 0.84 | SMN1; SMN2 (0.42) | LMNATP53ALDH1A1F10NPSR1 | |
| SCHEMBL5868300 | 0.84 | F10 (0.41) | THRBALDH1A1MEN1KMT2AF10 | |
| Hydrochloric Acid SCHEMBL5868209 | 0.83 | HDAC1 (0.38) | ALDH1A1MEN1KMT2AF10NPSR1 | |
| SCHEMBL6177113 | 0.81 | KMT2A (0.38) | ALDH1A1KMT2ACCR3F10KDM4E | |
| Hydrochloric Acid SCHEMBL4840285 | 0.80 | F10 (0.39) | F10HTR1AKDM4EL3MBTL1HPGD | |
| SCHEMBL6420537 | 0.79 | PKM (0.38) | LMNATHRBALDH1A1F10KDM4E | |
| SCHEMBL5868118 | 0.78 | F10 (0.39) | ALDH1A1F10NPSR1HTT | |
| SCHEMBL5868287 | 0.77 | CCR3 (0.39) | CCR3F10CHRM2 | |
| SCHEMBL5868222 | 0.77 | F10 (0.43) | LMNATP53F10NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053078-B2 | Serine protease inhibitors | ELI LILLY AND COMPANY (US) | 2006-05-30 | — | — | US | disclosed |