Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11856575 | 0.86 | RAB9A (0.65) | SMN1; SMN2RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL5868574 | 0.85 | RAB9A (0.49) | SMN1; SMN2RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL9292148 | 0.84 | RAB9A (0.54) | SMN1; SMN2RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL11856566 | 0.83 | RAB9A (0.61) | SMN1; SMN2RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL11852050 | 0.81 | RAB9A (0.62) | SMN1; SMN2RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL5868377 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL11856103 | 0.78 | RAB9A (0.59) | SMN1; SMN2RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL11858868 | 0.78 | RAB9A (0.59) | SMN1; SMN2RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL11862268 | 0.77 | RAB9A (0.57) | SMN1; SMN2RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL11857767 | 0.77 | RAB9A (0.57) | SMN1; SMN2RAB9AKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049343-B2 | Substituted hydrazine derivatives | MERCK & CO., INC. (US) | 2006-05-23 | — | — | US | disclosed |