SCHEMBL586919

SCHEMBL586919

[SiH3]c1ccc2cccc3c2c1-c1ccccc1-3

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
HSD17B10 Q99714 6/20 0.58
TSHR P16473 5/20 0.58
MAPK1 P28482 4/20 0.58
ATM Q13315 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
CASP1 P29466 3/20 0.47
CYP3A4 P08684 3/20 0.47
CASP7 P55210 2/20 0.47
DNMT1 P26358 2/20 0.47
PABPC1 P11940 1/20 0.47
HPGD P15428 4/20 0.46
HIF1A Q16665 2/20 0.46
TP53 P04637 1/20 0.46
CYP1A2 P05177 3/20 0.42
CYP1B1 Q16678 2/20 0.42
CYP1A1 P04798 1/20 0.42
KDM4E B2RXH2 1/20 0.41
THRB P10828 1/20 0.39
CES1 P23141 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31749078 0.82 ALDH1A1 (0.64) ALDH1A1HSD17B10TSHRMAPK1ATM
SCHEMBL5894722 0.77 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRMAPK1ATM
SCHEMBL29584259 0.77 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRMAPK1ATM
SCHEMBL29000574 0.77 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRMAPK1ATM
SCHEMBL6541611 0.77 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRMAPK1ATM
SCHEMBL5894727 0.77 HSD17B10 (0.56) ALDH1A1HSD17B10TSHRMAPK1ATM
SCHEMBL7560734 0.77 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRMAPK1ATM
SCHEMBL1059869 0.77 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRMAPK1ATM
SCHEMBL2450955 0.77 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRMAPK1ATM
SCHEMBL5190483 0.77 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2416954-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE Global OLED Technology LLC (US) 2012-02-15 EP claimed
WO-2010114838-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC (US) 2010-10-07 WO claimed
US-20100244677-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2010-09-30 US claimed
CN-102369102-A OLED device containing silyl fluoranthene derivatives GLOBAL OLED TECHNOLOGY LLC 2012-03-07 CN disclosed
CN-102369102-A OLED device containing silyl fluoranthene derivatives GLOBAL OLED TECHNOLOGY LLC 2012-03-07 CN disclosed
EP-2416954-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE Global OLED Technology LLC (US) 2012-02-15 EP disclosed
EP-2416954-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE Global OLED Technology LLC (US) 2012-02-15 EP disclosed
WO-2010114838-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC (US) 2010-10-07 WO disclosed
WO-2010114838-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC (US) 2010-10-07 WO disclosed
US-20100244677-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2010-09-30 US disclosed
US-20100244677-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2010-09-30 US disclosed