Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5869964 | 1.00 | ANPEP (0.44) | ANPEPHDAC1HDAC6CA12CA2 | |
| SCHEMBL5869969 | 1.00 | ANPEP (0.44) | ANPEPHDAC1HDAC6CA12CA2 | |
| SCHEMBL5869855 | 0.85 | CTSK (0.46) | ANPEPCA12CA2CA7CA9 | |
| SCHEMBL5869849 | 0.85 | CTSK (0.46) | ANPEPCA12CA2CA7CA9 | |
| SCHEMBL5869851 | 0.85 | CTSK (0.46) | ANPEPCA12CA2CA7CA9 | |
| SCHEMBL5870254 | 0.85 | CTSK (0.44) | HDAC1HDAC6CAPN1CTSKCTSL | |
| SCHEMBL5870261 | 0.85 | CTSK (0.44) | HDAC1HDAC6CAPN1CTSKCTSL | |
| SCHEMBL5870256 | 0.85 | CTSK (0.44) | HDAC1HDAC6CAPN1CTSKCTSL | |
| SCHEMBL5870377 | 0.84 | ANPEP (0.45) | ANPEPCA12CA2CA7CA9 | |
| SCHEMBL5870383 | 0.84 | ANPEP (0.45) | ANPEPCA12CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045532-B2 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-05-16 | — | — | US | disclosed |