Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.83 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.73 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.73 |
| ▸ | BACE1 | P56817 | 1/20 | 0.73 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.73 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.69 |
| ▸ | HRH1 | P35367 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951411 | 1.00 | LTA4H (0.83) | LTA4HPSMB1PSMB5BACE1HRH3 | |
| Hydrochloric Acid SCHEMBL8475600 | 0.98 | LTA4H (0.81) | LTA4HPSMB1PSMB5BACE1HRH3 | |
| Bromide SCHEMBL4827747 | 0.98 | LTA4H (0.81) | LTA4HPSMB1PSMB5BACE1HRH3 | |
| SCHEMBL255201 | 0.98 | LTA4H (0.86) | LTA4HPSMB1PSMB5BACE1HRH3 | |
| Ammonia Solution, Strong SCHEMBL264615 | 0.96 | LTA4H (0.83) | LTA4HPSMB1PSMB5BACE1HRH3 | |
| SCHEMBL14500223 | 0.92 | LTA4H (0.77) | LTA4HPSMB1PSMB5BACE1HRH3 | |
| Anisole SCHEMBL28200949 | 0.92 | LTA4H (0.71) | LTA4HPSMB1PSMB5BACE1HRH3 | |
| SCHEMBL7141714 | 0.91 | LTA4H (1.00) | LTA4HPSMB1PSMB5HRH3 | |
| SCHEMBL4084100 | 0.91 | HRH3 (0.87) | LTA4HHRH3HRH1KDM4EALDH1A1 | |
| SCHEMBL2823877 | 0.91 | HRH3 (0.87) | LTA4HHRH3HRH1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |
| US-7105679-B2 | Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators | KANOJIA RAMESH M | 2006-09-12 | — | — | US | disclosed |