Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.59 |
| ▸ | CNR2 | P34972 | 12/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14433904 | 0.90 | CNR1 (0.71) | CNR1CNR2KCNH2 | |
| SCHEMBL5240453 | 0.86 | CNR1 (0.61) | CNR1CNR2 | |
| SCHEMBL5239405 | 0.85 | CNR1 (0.78) | CNR1CNR2KCNH2 | |
| SCHEMBL5236352 | 0.82 | CNR1 (0.81) | CNR1CNR2KCNH2 | |
| SCHEMBL5870775 | 0.81 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL5237152 | 0.80 | CNR1 (0.56) | CNR1CNR2KCNH2 | |
| SCHEMBL20304782 | 0.77 | CNR1 (0.79) | CNR1CNR2KCNH2 | |
| SCHEMBL15200732 | 0.76 | CNR1 (0.77) | CNR1CNR2KCNH2 | |
| SCHEMBL31038572 | 0.76 | CNR1 (0.77) | CNR1CNR2KCNH2 | |
| SCHEMBL20304728 | 0.74 | CNR1 (1.00) | CNR1CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129239-B2 | Purine compounds and uses thereof | PFIZER INC. (US) | 2006-10-31 | — | — | US | disclosed |
| US-20060241120-A1 | Cannabinoid Receptor Ligands and Uses Thereof | PFIZER INC | 2006-10-26 | — | — | US | disclosed |
| US-20040092520-A1 | Purine compounds and uses thereof | PFIZER INC. | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241120-A1 | Cannabinoid Receptor Ligands and Uses Thereof | CNR1, CNR2, GPR18 | CNR1 1/4885CNR2 2/4885KCNH2 2953/4885 |
| US-20040092520-A1 | Purine compounds and uses thereof | CNR1, CNR2, P2RY1 | CNR1 1/4885CNR2 2/4885KCNH2 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.