Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014504 | 0.85 | TSHR (0.43) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1009799 | 0.79 | TSHR (0.36) | TSHR | |
| SCHEMBL7101860 | 0.72 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1011642 | 0.70 | TSHR (0.43) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1012651 | 0.69 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL23248662 | 0.69 | TSHR (0.49) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1779326 | 0.67 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1501363 | 0.67 | TSHR (0.54) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Acetic Acid SCHEMBL3361156 | 0.66 | TSHR (0.70) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8900217 | 0.66 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045572-B2 | Organosilicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-05-16 | — | — | US | disclosed |
| US-20050101791-A1 | Organosilicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-05-12 | — | — | US | disclosed |
| US-6849755-B2 | Organosilicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101791-A1 | Organosilicon compound | H1-0, H1-2, H1-4 | TSHR 2447/4885ALDH1A1 3552/4885TP53 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.