SCHEMBL1779326

SCHEMBL1779326

C=CC(=O)OCCO[SiH](C)C

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.59
ALDH1A1 P00352 5/20 0.59
TP53 P04637 3/20 0.59
HIF1A Q16665 3/20 0.59
HSD17B10 Q99714 1/20 0.59
CYP3A4 P08684 2/20 0.54
HPGD P15428 1/20 0.53
THRB P10828 4/20 0.49
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ATM Q13315 1/20 0.33
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230693 0.88 TSHR (0.67) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL537087 0.88 TSHR (0.61) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL26918628 0.86 TSHR (0.70) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL93462 0.82 TSHR (0.84) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL30604742 0.82 TSHR (0.84) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL3835483 0.80 TSHR (0.55) TSHRALDH1A1TP53HIF1AHSD17B10
Propene SCHEMBL11227474 0.80 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
Propane SCHEMBL6904776 0.80 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL14505377 0.80 TSHR (0.55) TSHRALDH1A1TP53HIF1AHSD17B10
Ethylene SCHEMBL1165263 0.79 TSHR (0.80) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
CN-111533854-B Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2023-03-31 CN disclosed
CN-109803826-B Laminate and method for producing same 信越化学工业株式会社 2021-05-11 CN disclosed
CN-108472685-B Method for producing laminate 信越化学工业株式会社 2021-02-02 CN disclosed
CN-111533854-A Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2020-08-14 CN disclosed
EP-3045506-B1 ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE SHINETSU CHEMICAL CO (JP) 2020-03-04 EP disclosed
US-20190291394-A1 LAMINATED BODY AND PRODUCTION METHOD THEREFOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-09-26 US disclosed
EP-3527366-A1 LAMINATED BODY AND PRODUCTION METHOD THEREFOR Shin-Etsu Chemical Co., Ltd. (JP) 2019-08-21 EP disclosed
US-10196409-B2 Organosilicon compound and curable composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-02-05 US disclosed
EP-3210988-B1 ORGANOSILICON COMPOUND AND CURABLE COMPOSITION SHINETSU CHEMICAL CO (JP) 2018-06-20 EP disclosed
US-20100184907-A1 PRODUCTION OF A COMPOSITE COMPRISING INORGANIC MATERIAL AND ORGANIC POLYMER WACKER CHEMIE AG (DE) 2010-07-22 US disclosed
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-20070299231-A1 POLYSILOXANES CONTAINING (METH)ACRYLIC ESTER GROUPS ATTACHED VIA SiOC GROUPS, PROCESSES FOR PREPARING THEM AND THEIR USE AS A RADIATION-CURABLE ADHESIVE COATING GOLDSCHMIDT GMBH (DE) 2007-12-27 US disclosed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
US-5009986-A Solubility in organic solvents, durability, compatibility with polymers TEIJIN LIMITED (JP) 1991-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885TP53 4663/4885
US-10196409-B2 Organosilicon compound and curable composition MASTL, PIEZO1, MCM6 TSHR 3198/4885ALDH1A1 1875/4885TP53 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.