SCHEMBL5872595

SCHEMBL5872595

[O]C1OCCCC1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16827257 0.72
SCHEMBL4353199 0.68
SCHEMBL6201883 0.68
SCHEMBL6702605 0.68
SCHEMBL2356896 0.68
SCHEMBL3043857 0.67 EPHX1 (0.43)
SCHEMBL919567 0.67
SCHEMBL2007501 0.65
SCHEMBL22804154 0.65
SCHEMBL7390 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7087746-B2 Functionalised maltosyl fluoride as glycosyl donor in the chemo-enzymatic preparation of ratio of oligo-or polysaccharides CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2006-08-08 US disclosed
US-20040176317-A1 Functionalised maltosyl fluoride as glycosyl donor in the chemo-enzymatic preparation of ratio of oligo-or polysaccharides CENTRE NATIONAL DE LA RECHERCHE, SCIENTIFIQUE (C.N.R.S.) (FR) 2004-09-09 US disclosed
EP-1409499-A1 FUNCTIONALISED MALTOSYL FLUORIDE AS GLYCOSYL DONOR IN THE CHEMO-ENZYMATIC PREPARATION OF OLIGO- OR POLYSACCHARIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2004-04-21 EP disclosed
WO-2003010178-A1 FUNCTIONALISED MALTOSYL FLUORIDE AS GLYCOSYL DONOR IN THE CHEMO-ENZYMATIC PREPARATION OF OLIGO- OR POLYSACCHARIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2003-02-06 WO disclosed
US-6410748-B1 Alicycli c group-containing monomer KABUSHIKI KAISHA TOSHIBA (JP) 2002-06-25 US disclosed
US-6291129-B1 LIGHT SENSITIVE ELEMENT WITH UNSATURATED POLYMERS KABUSHIKI KAISHA TOSHIBA (JP) 2001-09-18 US disclosed
US-5760042-A INHIBITOR OF PHOSPHODIESTERASES SANKYO COMPANY, LIMITED (JP) 1998-06-02 US disclosed
US-5616600-A Griseolic acid compounds and their use as a phosphodiesterase inhibitor SANKYO COMPANY, LIMITED (JP) 1997-04-01 US disclosed
US-5556975-A CYCLIC GMP PHOSPHODIESTERASE INHIBITOR SANKYO COMPANY, LIMITED (JP) 1996-09-17 US disclosed
US-5532369-A NUCLEOTIDE INHIBITORS OF PHOSPHODIESTERASE SANKYO COMPANY, LIMITED (JP) 1996-07-02 US disclosed
US-5498819-A INHIBITORS OF PHOSPHODIESTERASE AS NEUROTROPIC AGENTS, ANTIINFLAMMATORY AGENTS, MUSCLE RELAXANTS, ANTICARCINOGENIC AGENTS AND ANTIDIABETIC AGENTS SANKYO COMPANY, LIMITED (JP) 1996-03-12 US disclosed
EP-0318060-B1 Griseolic acid derivatives, their preparation and their use SANKYO CO (JP) 1995-10-25 EP disclosed
EP-0319050-B1 Griseolic acid derivatives, their preparation and their use SANKYO CO (JP) 1995-04-12 EP disclosed
EP-0214708-B1 GRISEOLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE SANKYO COMPANY LIMITED (JP) 1989-12-13 EP disclosed
EP-0319050-A2 Griseolic acid derivatives, their preparation and their use SANKYO COMPANY LIMITED (JP) 1989-06-07 EP disclosed
EP-0318060-A2 Griseolic acid derivatives, their preparation and their use Sankyo Company Limited (JP) 1989-05-31 EP disclosed
EP-0214708-A2 Griseolic acid derivatives, their preparation and their use SANKYO COMPANY LIMITED (JP) 1987-03-18 EP disclosed