Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816249 | 0.83 | CYP3A4 (0.50) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL8990193 | 0.80 | CYP3A4 (0.47) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL1274550 | 0.77 | CYP3A4 (0.46) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL1275503 | 0.75 | CYP3A4 (0.43) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL10685560 | 0.74 | CYP3A4 (0.53) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL27263495 | 0.74 | ALDH1A1 (0.48) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL5930242 | 0.73 | CYP3A4 (0.70) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL27532558 | 0.72 | RECQL (0.47) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL3500694 | 0.72 | CYP3A4 (0.47) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL10449652 | 0.72 | CYP3A4 (0.52) | TSHRCYP3A4TDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7056967-B2 | Stabilized medium and high voltage cable insulation composition | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-06-06 | — | — | US | disclosed |
| EP-1326915-B1 | POLYOLEFIN ARTICLES WITH LONG-TERM ELEVATED TEMPERATURE STABILITY | CLARIANT FINANCE BVI LTD (VG) | 2005-11-09 | — | — | EP | disclosed |
| US-6774170-B2 | HEAT STABILIZING WITH AN OXIDIZED, NON-CATIONIZED, NON-SILYLATED SULFUR BLACK PIGMENT, A HINDERED PHENOLIC ANTIOXIDANT A SULFUR-CONTAINING SECONDARY STABILIZER, AND A HINDERED AMINE | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-08-10 | — | — | US | disclosed |
| EP-1326915-A2 | POLYOLEFIN ARTICLES WITH LONG-TERM ELEVATED TEMPERATURE STABILITY | Clariant Finance (BVI) Limited (VG) | 2003-07-16 | — | — | EP | disclosed |
| US-6538056-B1 | Polyethylene or polypropylene compounded with sulfur black pigment; sterically hindered phenolic antioxidant and sulfur compound stabilizer; heat resistance | CLARIANT INTERNATIONAL LTD. (CH) | 2003-03-25 | — | — | US | disclosed |
| US-20020198344-A1 | Stabilized medium and high voltage cable insulation composition | CIBA SPECIALTY CHEMICALS CORP. | 2002-12-26 | — | — | US | disclosed |
| US-20020156165-A1 | Polyolefin articles with long-term elevated temperature stability | CLARIANT INTERNATIONAL LTD. | 2002-10-24 | — | — | US | disclosed |
| EP-1249845-A2 | Stabilized medium and high voltage cable insulation composition | Ciba SC Holding AG (CH) | 2002-10-16 | — | — | EP | disclosed |
| WO-2002031043-A2 | POLYOLEFIN ARTICLES WITH LONG-TERM ELEVATED TEMPERATURE STABILITY | CLARIANT FINANCE (BVI) LIMITED (VG) | 2002-04-18 | — | — | WO | disclosed |
| EP-0273013-B2 | Substituted phenols as stabilizers | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | disclosed |
| US-5427701-A | Heat and oxidation resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| US-5376290-A | For elastomers; heat and oxidation resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| US-5008459-A | For elastomers; registance to heat aging | CIBA-GEIGY CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0273013-A1 | Substituted phenols as stabilizers | CIBA-GEIGY AG (CH) | 1988-06-29 | — | — | EP | disclosed |