Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.60 |
| ▸ | CTSK | P43235 | 6/20 | 0.60 |
| ▸ | CTSB | P07858 | 2/20 | 0.60 |
| ▸ | CTSL | P07711 | 2/20 | 0.60 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764798 | 0.86 | CTSS (0.64) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL6162474 | 0.86 | CTSS (0.64) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL5403879 | 0.85 | CTSS (0.58) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL6019868 | 0.84 | CTSS (0.66) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL6790744 | 0.84 | CTSS (0.66) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL4654379 | 0.84 | CTSS (0.61) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL4654386 | 0.84 | CTSS (0.61) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL5408861 | 0.83 | CTSS (0.56) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL6832948 | 0.83 | CTSS (0.67) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL10174993 | 0.83 | CTSS (0.67) | CTSSCTSKCTSBCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045360-B2 | Method for analysis of reaction products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-05-16 | — | — | US | disclosed |
| US-20020090728-A1 | Method for analysis of reaction products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-07-11 | — | — | US | disclosed |