Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873425 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL4994907 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL15244828 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL24648736 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL12966021 | 0.87 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL31421469 | 0.87 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL9371448 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL20061841 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL7398961 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL32668285 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1HSD17B10NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045360-B2 | Method for analysis of reaction products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-05-16 | — | — | US | disclosed |
| US-20020090728-A1 | Method for analysis of reaction products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-07-11 | — | — | US | disclosed |
| WO-2001057526-A1 | METHOD FOR ANALYSIS OF REACTION PRODUCTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2001-08-09 | — | — | WO | disclosed |