Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398961 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL15244828 | 0.87 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL4994907 | 0.87 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL1429928 | 0.87 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL1256350 | 0.87 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL24648736 | 0.87 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL20061874 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL11585903 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL5873415 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL5873425 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105512-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-19 | — | — | US | disclosed |
| US-20180105512-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105512-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | TPSD1, TPSAB1, TMSB4X | SMN1; SMN2 790/4885ALDH1A1 2197/4885NPC1 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.