SCHEMBL5873438

SCHEMBL5873438

OC(c1ccccc1)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
LMNA P02545 4/20 0.39
MAPK1 P28482 2/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
TSHR P16473 2/20 0.38
ALOX15 P16050 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565029 0.79 CES2 (0.44) SMN1; SMN2HPGDL3MBTL1LMNAMAPK1
Diphenylmethanol SCHEMBL11564700 0.76 SMN1; SMN2 (0.61) SMN1; SMN2L3MBTL1LMNAMAPK1TSHR
Diphenylmethanol SCHEMBL10868602 0.76 SMN1; SMN2 (0.61) SMN1; SMN2L3MBTL1LMNAMAPK1TSHR
Diphenylmethanol SCHEMBL6434457 0.76 SMN1; SMN2 (0.61) SMN1; SMN2L3MBTL1LMNAMAPK1TSHR
Diphenylmethanol SCHEMBL41571 0.76 SMN1; SMN2 (0.61) SMN1; SMN2L3MBTL1LMNAMAPK1TSHR
Diphenylmethanol SCHEMBL15641329 0.73 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1LMNAMAPK1TSHR
Diphenylmethanol SCHEMBL8164003 0.73 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1LMNAMAPK1TSHR
SCHEMBL8671295 0.73 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1LMNAMAPK1TSHR
Diphenylmethanol SCHEMBL9324200 0.73 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1LMNAMAPK1TSHR
Diphenylmethanol SCHEMBL29571414 0.73 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1LMNAMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-5897940-A Ink jet transparencies XEROX CORPORATION (US) 1999-04-27 US claimed
EP-0677076-B1 DIARYL CARBINOL METATHESIS CATALYSTS SHELL OIL CO (US) 1997-04-16 EP claimed
EP-0677076-A1 DIARYL CARBINOL METATHESIS CATALYSTS. SHELL OIL CO (US) 1995-10-18 EP claimed
WO-1994015989-A1 DIARYL CARBINOL METATHESIS CATALYSTS SHELL OIL COMPANY (US) 1994-07-21 WO claimed
US-5276118-A Metal complex SHELL OIL COMPANY (US) 1994-01-04 US claimed
EP-3254860-B1 RECORDING MATERIAL AND RECORDING SHEET NIPPON SODA CO (JP) 2020-11-04 EP disclosed
US-10226957-B2 Recording material and recording sheet NIPPON SODA CO., LTD. (JP) 2019-03-12 US disclosed
US-20180022137-A1 RECORDING MATERIAL AND RECORDING SHEET NIPPON SODA CO., LTD. (JP) 2018-01-25 US disclosed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US disclosed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US disclosed
US-5922117-A Ink compositions containing alcohols XEROX CORPORATION (US) 1999-07-13 US disclosed
US-5213710-A Benzene derivatives and a liquid-crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-05-25 US disclosed
EP-0377649-B1 HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION Hewlett-Packard Company (US) 1993-03-10 EP disclosed
US-5114768-A Electrophoretic protein separation HEWLETT-PACKARD COMPANY (US) 1992-05-19 US disclosed
EP-0452055-A1 Surfaces with reduced protein interactions Hewlett-Packard Company (US) 1991-10-16 EP disclosed
US-5006313-A Halogenated surface with reduced protein interaction HEWLETT-PACKARD COMPANY (US) 1991-04-09 US disclosed
EP-0377649-A1 HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION. HEWLETT PACKARD CO (US) 1990-07-18 EP disclosed
WO-1989012225-A1 HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION HEWLETT-PACKARD COMPANY (US) 1989-12-14 WO disclosed