Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.46 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.46 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.46 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.46 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321294 | 0.96 | ALDH1A1 (0.69) | ALDH1A1MAOAKMOALOX5CYP1A2 | |
| SCHEMBL19618929 | 0.93 | ALDH1A1 (0.64) | ALDH1A1MAOAKMOALOX5CYP1A2 | |
| SCHEMBL14481975 | 0.93 | ALDH1A1 (0.64) | ALDH1A1MAOAKMOALOX5CYP1A2 | |
| SCHEMBL8452262 | 0.92 | ALDH1A1 (0.75) | ALDH1A1MAOAKMOALOX5BACE1 | |
| SCHEMBL4332773 | 0.92 | ALDH1A1 (0.75) | ALDH1A1MAOAKMOALOX5BACE1 | |
| SCHEMBL481505 | 0.92 | ALDH1A1 (0.75) | ALDH1A1MAOAKMOALOX5BACE1 | |
| SCHEMBL2401076 | 0.88 | ALDH1A1 (0.69) | ALDH1A1MAOAKMOALOX5CYP3A4 | |
| SCHEMBL2731883 | 0.88 | ALDH1A1 (0.69) | ALDH1A1MAOAKMOALOX5CYP3A4 | |
| SCHEMBL5130299 | 0.88 | ALDH1A1 (0.69) | ALDH1A1MAOAKMOALOX5CYP1A2 | |
| SCHEMBL31734209 | 0.88 | ALDH1A1 (0.69) | ALDH1A1MAOAKMOALOX5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034174-B2 | Mono-, oligo- and polymers comprising a 2,6-azulene group and their use as charge transport materials | MERCK PATENT GMBH (DE) | 2006-04-25 | — | — | US | disclosed |
| EP-1318183-B1 | Oligomers and Polymers comprising a 2,6-azulene group and their use as charge transport materials | MERCK PATENT GMBH (DE) | 2005-05-18 | — | — | EP | disclosed |
| US-20030122479-A1 | Mono-, oligo- and polymers comprising a 2,6-azulene group and their use as charge transport materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-07-03 | — | — | US | disclosed |
| EP-1318183-A1 | Mono,- oligo- and polymers comprising a 2,6-azulene group and their use as charge transport materials | MERCK PATENT GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030122479-A1 | Mono-, oligo- and polymers comprising a 2,6-azulene group and their use as charge transport materials | PARN, PARG, SLCO2A1 | ALDH1A1 2598/4885MAOA 1048/4885KMO 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.