Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.61 |
| ▸ | FPR1 | P21462 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873506 | 0.89 | MCHR1 (0.65) | MCHR1 | |
| SCHEMBL5873508 | 0.87 | MCHR1 (0.81) | MCHR1 | |
| SCHEMBL5873547 | 0.87 | MCHR1 (0.52) | MCHR1 | |
| SCHEMBL5873691 | 0.83 | KDM4E (0.47) | MCHR1 | |
| SCHEMBL5873571 | 0.78 | MCHR1 (0.76) | MCHR1 | |
| SCHEMBL12528867 | 0.78 | MCHR1 (0.67) | MCHR1FPR1FPR2 | |
| SCHEMBL5873634 | 0.78 | MCHR1 (0.75) | MCHR1 | |
| SCHEMBL5873553 | 0.77 | MCHR1 (0.73) | MCHR1 | |
| SCHEMBL5873569 | 0.76 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL12528929 | 0.75 | FPR1 (0.60) | MCHR1FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084156-B2 | 2-Aminoquinoline compounds | MERCK & CO., INC. (US) | 2006-08-01 | — | — | US | claimed |
| US-20050026915-A1 | 2-Aminoquinoline compounds | MERCK SHARP & DOHME CORP. | 2005-02-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026915-A1 | 2-Aminoquinoline compounds | MCHR1, MCHR2, MC5R | MCHR1 1/4885FPR1 677/4885FPR2 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.