Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1481169 | 0.91 | DHODH (0.38) | DHODHKCNA3PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1481173 | 0.91 | DHODH (0.38) | DHODHKCNA3PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1480586 | 0.90 | PPARA (0.46) | PPARAALBFFAR1PPARGPPARD | |
| SCHEMBL1480587 | 0.90 | PPARA (0.46) | PPARAALBFFAR1PPARGPPARD | |
| SCHEMBL5873687 | 0.90 | HDAC3 (0.33) | PPARAALBFFAR1PPARGPPARD | |
| SCHEMBL1480591 | 0.87 | FFAR4 (0.43) | PPARAALBFFAR1PPARGPPARD | |
| SCHEMBL1480594 | 0.87 | FFAR4 (0.43) | PPARAALBFFAR1PPARGPPARD | |
| SCHEMBL1480271 | 0.83 | DHODH (0.36) | DHODHHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1480268 | 0.83 | DHODH (0.36) | DHODHHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1481647 | 0.82 | PTGS2 (0.41) | PPARAHDAC3STAT3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006518738-A | — | — | 2006-08-17 | — | — | JP | claimed |
| EP-1594847-A2 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Transtech Pharma, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| WO-2004071447-A9 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC (US) | 2005-10-13 | — | — | WO | claimed |
| WO-2004071447-A2 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC. (US) | 2004-08-26 | — | — | WO | claimed |