Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29368068 | 0.95 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| Potassium Ion SCHEMBL30466772 | 0.95 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL30033020 | 0.95 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL9888371 | 0.95 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL1588805 | 0.95 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL12234418 | 0.95 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL2238091 | 0.95 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| Lithium Ion SCHEMBL1457859 | 0.95 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| Silver SCHEMBL1177403 | 0.95 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL30079649 | 0.95 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180161365-A1 | Phosphate-Binding Magnesium Salts And Uses Thereof | CURRAX PHARMACEUTICALS LLC | 2018-06-14 | — | — | US | claimed |
| US-9889157-B2 | Phosphate-binding magnesium salts and uses thereof | CYPRESS PHARMACEUTICALS, INC. (US) | 2018-02-13 | — | — | US | claimed |
| US-20170202875-A1 | Phosphate-Binding Magnesium Salts And Uses Thereof | WILMINGTON SAVINGS FUND SOCIETY, FSB | 2017-07-20 | — | — | US | claimed |
| US-9610267-B2 | Phosphate-binding magnesium salts and uses thereof | CYPRESS PHARMACEUTICALS, INC. (US) | 2017-04-04 | — | — | US | claimed |
| US-20160256420-A1 | Phosphate-Binding Magnesium Salts And Uses Thereof | WILMINGTON SAVINGS FUND SOCIETY, FSB | 2016-09-08 | — | — | US | claimed |
| US-9339481-B2 | Phosphate-binding magnesium salts and uses thereof | CYPRESS PHARMACEUTICALS, INC. (US) | 2016-05-17 | — | — | US | claimed |
| EP-2416786-A1 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | Cypress Pharmaceutical, Inc. (US) | 2012-02-15 | — | — | EP | claimed |
| WO-2010117370-A1 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | CYPRESS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | claimed |
| US-20090269399-A1 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | CYPRESS PHARMACEUTICAL, INC. (US) | 2009-10-29 | — | — | US | claimed |
| US-20180161365-A1 | Phosphate-Binding Magnesium Salts And Uses Thereof | CURRAX PHARMACEUTICALS LLC | 2018-06-14 | — | — | US | disclosed |
| US-9889157-B2 | Phosphate-binding magnesium salts and uses thereof | CYPRESS PHARMACEUTICALS, INC. (US) | 2018-02-13 | — | — | US | disclosed |
| US-20170202875-A1 | Phosphate-Binding Magnesium Salts And Uses Thereof | WILMINGTON SAVINGS FUND SOCIETY, FSB | 2017-07-20 | — | — | US | disclosed |
| US-9610267-B2 | Phosphate-binding magnesium salts and uses thereof | CYPRESS PHARMACEUTICALS, INC. (US) | 2017-04-04 | — | — | US | disclosed |
| US-20160256420-A1 | Phosphate-Binding Magnesium Salts And Uses Thereof | WILMINGTON SAVINGS FUND SOCIETY, FSB | 2016-09-08 | — | — | US | disclosed |
| WO-2011050042-A1 | THERMOPLASTIC POLYMER COMPOSITION | MILLIKEN & COMPANY (US) | 2011-04-28 | — | — | WO | disclosed |
| US-20110092625-A1 | THERMOPLASTIC POLYMER COMPOSITION | MILLKEN & COMPANY | 2011-04-21 | — | — | US | disclosed |
| US-20110045063-A2 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | CYPRESS PHARMACEUTICAL, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| WO-2010117370-A1 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | CYPRESS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20090269399-A1 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | CYPRESS PHARMACEUTICAL, INC. (US) | 2009-10-29 | — | — | US | disclosed |
| US-5373064-A | Process for producing chlorinated polyolefin in an aqueous suspension system comprising a metal salt of an alkyldiphenyl ether disulfonic acid | SHOWA DENKO K.K. (JP) | 1994-12-13 | — | — | US | disclosed |