Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235939 | 0.84 | BACE1 (0.48) | BACE1PTGDR2CNR1CNR2 | |
| SCHEMBL4665186 | 0.81 | BACE1 (0.50) | BACE1PTGDR2 | |
| SCHEMBL3448725 | 0.76 | PTGDR2 (0.49) | BACE1PTGDR2ACLY | |
| SCHEMBL16395376 | 0.75 | BACE1 (0.47) | BACE1PTGDR2CNR1CNR2 | |
| SCHEMBL16394911 | 0.74 | BACE1 (0.46) | BACE1PTGDR2CNR1CNR2 | |
| SCHEMBL14173157 | 0.74 | BACE1 (0.49) | BACE1PTGDR2CNR1CNR2 | |
| SCHEMBL12438736 | 0.73 | BACE1 (0.58) | BACE1PTGDR2 | |
| SCHEMBL14173094 | 0.73 | BACE1 (0.45) | BACE1PTGDR2CNR1CNR2 | |
| SCHEMBL1162218 | 0.73 | CYP2C9 (0.46) | BACE1 | |
| SCHEMBL11615389 | 0.72 | PTGDR2 (0.49) | BACE1PTGDR2ACLYCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091302-B2 | Process for the preparation of polycarbonate | BAYER MATERIALSCIENCE AG (DE) | 2006-08-15 | — | — | US | disclosed |
| US-20050239995-A1 | Process for the preparation of polycarbonate | BAYER MATERIALSCIENCE AG | 2005-10-27 | — | — | US | disclosed |