SCHEMBL4665186

SCHEMBL4665186

CC(C)(C)c1ccc(OC(=O)O)c(-c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.50
PTGDR2 Q9Y5Y4 4/20 0.49
L3MBTL1 Q9Y468 2/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
PLA2G1B P04054 1/20 0.44
NFKB1 P19838 1/20 0.44
CASP3 P42574 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
ATG4B Q9Y4P1 1/20 0.44
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP2C19 P33261 1/20 0.42
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235939 0.88 BACE1 (0.48) BACE1PTGDR2ALDH1A1
SCHEMBL3448725 0.88 PTGDR2 (0.49) BACE1PTGDR2
Biphenyl SCHEMBL20514294 0.86 RXRA (0.46) BACE1L3MBTL1RAB9AMAPTTDP1
SCHEMBL19739518 0.83 L3MBTL1 (0.50) BACE1PTGDR2L3MBTL1NPC1ALDH1A1
SCHEMBL237517 0.83 NPSR1 (0.49) BACE1L3MBTL1ALDH1A1RAB9AMAPT
SCHEMBL29949950 0.83 NPSR1 (0.49) BACE1L3MBTL1ALDH1A1RAB9AMAPT
SCHEMBL5873764 0.81 BACE1 (0.42) BACE1PTGDR2
Benzamide SCHEMBL21771941 0.81 MAPT (0.51) BACE1PTGDR2L3MBTL1MAPTTDP1
SCHEMBL19739517 0.80 L3MBTL1 (0.46) BACE1L3MBTL1NPC1ALDH1A1PLA2G1B
SCHEMBL7642039 0.79 MAPT (0.47) L3MBTL1NPC1ALDH1A1PLA2G1BNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104640837-B Method using vapor recompression for continuously preparing aryl carbonate Arrcostab and/or diaryl carbonate 沙特基础全球技术有限公司 2018-09-25 CN disclosed
CN-105714282-A Method and apparatus for producing polycarbonate 拜尔材料科学股份公司 2016-06-29 CN disclosed
CN-102102204-B Method and apparatus for producing polycarbonate BAYER MATERIALSCIENCE AG (DE) 2016-04-27 CN disclosed
CN-105189445-A Purification method of diphenyl carbonate for preparing high quality polycarbonate SABIC INNOVATIVE PLASTICS IP 2015-12-23 CN disclosed
CN-104640837-A Process for the continuous manufacture of aryl alkyl carbonate and/or diaryl carbonate using vapor recompression SABIC INNOVATIVE PLASTICS IP 2015-05-20 CN disclosed
CN-101607908-B Process for preparing diaryl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG 2014-07-23 CN disclosed
CN-101423473-B Method for producing diaryl carbonates and/or alkylaryl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG 2014-06-18 CN disclosed
CN-102102204-A Method and apparatus for producing polycarbonate BAYER MATERIALSCIENCE AG 2011-06-22 CN disclosed
CN-1972983-B Method for producing polycarbonate BAYER MATERIALSCIENCE AG 2011-06-15 CN disclosed
CN-101607908-A Process for preparing diaryl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG (DE) 2009-12-23 CN disclosed
WO-2000037531-A1 METHOD FOR THE PREPARATION OF BISPHENOL-A POLYCARBONATE WITH REDUCED LEVELS OF FRIES GENERAL ELECTRIC COMPANY (US) 2000-06-29 WO disclosed
WO-2000026276-A2 METHOD OF MANUFACTURING POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2000-05-11 WO disclosed
EP-0736558-A2 A polyester polycarbonate composition which is transparent and has outstanding thermal stability GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
EP-0694582-A2 A glass-fiber-reinforced polycarbonate resin composition GENERAL ELECTRIC COMPANY (US) 1996-01-31 EP disclosed
EP-0694581-A2 A polycarbonate resin composition GENERAL ELECTRIC COMPANY (US) 1996-01-31 EP disclosed
US-5418269-A Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks GE PLASTICS JAPAN (JP) 1995-05-23 US disclosed
EP-0605157-A2 Resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed