Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588006 | 0.94 | GAA (0.44) | GAAMAPK1ALDH1A1LMNAUSP2 | |
| SCHEMBL6489572 | 0.86 | GAA (0.41) | GAAMAPK1ALDH1A1LMNAHTT | |
| SCHEMBL587146 | 0.86 | MAPK1 (0.43) | GAAMAPK1ALDH1A1LMNATP53 | |
| SCHEMBL587431 | 0.86 | MAPK1 (0.43) | GAAMAPK1ALDH1A1LMNATP53 | |
| SCHEMBL587873 | 0.83 | MAPK1 (0.37) | GAAMAPK1LMNATP53MEN1 | |
| SCHEMBL6491274 | 0.83 | MAPK1 (0.36) | GAAMAPK1LMNATP53MEN1 | |
| SCHEMBL587100 | 0.82 | TP53 (0.44) | GAAMAPK1ALDH1A1LMNATP53 | |
| SCHEMBL6481693 | 0.82 | MAPK1 (0.35) | GAAMAPK1LMNAHTTTP53 | |
| SCHEMBL587233 | 0.82 | MAPK1 (0.41) | GAAMAPK1ALDH1A1LMNATP53 | |
| SCHEMBL587534 | 0.82 | MAPK1 (0.41) | GAAMAPK1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081925-B1 | Benzoylpyrazoles, their use as herbicides, and intermediates | BAYER CROPSCIENCE AG (DE) | 2012-02-15 | — | — | EP | disclosed |
| US-8084398-B2 | Benzoylpyrazoles and herbicide | BAYER CROPSCIENCE AG (DE) | 2011-12-27 | — | — | US | disclosed |
| US-8084398-B2 | Benzoylpyrazoles and herbicide | BAYER CROPSCIENCE AG (DE) | 2011-12-27 | — | — | US | disclosed |
| US-8084398-B2 | Benzoylpyrazoles and herbicide | BAYER CROPSCIENCE AG (DE) | 2011-12-27 | — | — | US | disclosed |
| US-20100094023-A1 | BENZOYLPYRAZOLES AND HERBICIDE | BAYER CROPSCIENCE AG (DE) | 2010-04-15 | — | — | US | disclosed |
| US-20100094023-A1 | BENZOYLPYRAZOLES AND HERBICIDE | BAYER CROPSCIENCE AG (DE) | 2010-04-15 | — | — | US | disclosed |
| US-20100094023-A1 | BENZOYLPYRAZOLES AND HERBICIDE | BAYER CROPSCIENCE AG (DE) | 2010-04-15 | — | — | US | disclosed |
| EP-2081925-A1 | BENZOYLPYRAZOLES, THEIR USE AS AS HERBICIDES, AND INTERMEDIATES | Bayer CropScience AG (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008043456-A1 | BENZOYLPYRAZOLES, THEIR USE AS AS HERBICIDES, AND INTERMEDIATES | BAYER CROPSCIENCE AG (DE) | 2008-04-17 | — | — | WO | disclosed |
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | YANAGI AKIHIKO (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1476437-A1 | NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES | Bayer CropScience AG (DE) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003066607-A1 | NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094023-A1 | BENZOYLPYRAZOLES AND HERBICIDE | ATL3, AHR, HACL2 | GAA 2641/4885MAPK1 2176/4885ALDH1A1 1178/4885 |
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | DDT, TTI1, CYP1A1 | GAA 2538/4885MAPK1 2914/4885ALDH1A1 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.