SCHEMBL587397

SCHEMBL587397

c1cc2cccc3c4cccc5cccc(c(c1)c23)c54.c1ccc2cc3c(ccc4cc5ccccc5cc43)cc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.65
ERBB2 P04626 1/20 0.65
FYN P06241 1/20 0.65
MAOA P21397 1/20 0.65
ACHE P22303 1/20 0.65
AHR P35869 1/20 0.65
ALDH1A1 P00352 11/20 0.61
HSD17B10 Q99714 9/20 0.61
HPGD P15428 6/20 0.61
HIF1A Q16665 4/20 0.61
CYP1B1 Q16678 2/20 0.61
THRB P10828 1/20 0.61
TSHR P16473 4/20 0.48
CASP1 P29466 3/20 0.48
MAPK1 P28482 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CYP3A4 P08684 3/20 0.46
CYP1A1 P04798 1/20 0.46
CASP7 P55210 2/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27529248 0.96 ALDH1A1 (0.70) CYP1A2ERBB2FYNMAOAACHE
Anthracene SCHEMBL5478607 0.90 ALDH1A1 (0.65) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4854111 0.89 ALDH1A1 (0.67) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4846794 0.89 HSD17B10 (0.60) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4850461 0.89 HSD17B10 (0.60) CYP1A2ERBB2FYNMAOAACHE
Pyrene SCHEMBL10523104 0.88 ALDH1A1 (0.73) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4851855 0.88 CYP1A2 (0.57) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4856657 0.88 HSD17B10 (0.65) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4851988 0.88 ALDH1A1 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4847644 0.87 ALDH1A1 (0.55) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103930471-A Flexible polyamines, flexible amine-terminated adducts, compositions thereof, and methods of use PRC DESOTO INT INC 2014-07-16 CN disclosed
CN-103930458-A Sulfur-containing polyureas and methods of use thereof PRC DESOTO INT INC 2014-07-16 CN disclosed
CN-103154716-A Analyte sensor SENOVA SYSTEMS INC 2013-06-12 CN disclosed
CN-101171012-B Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses RIGEL PHARMACEUTICALS INC 2013-04-17 CN disclosed
CN-102933081-A Sweet flavor modifier SENOMYX INC 2013-02-13 CN disclosed
CN-102918037-A Carbazole compound having substituent containing electron-accepting nitrogen-containing heteroaryl group, and organic electroluminescent element JNC CORP 2013-02-06 CN disclosed
CN-102917589-A Compositions comprising enzyme-cleavable opioid prodrugs and inhibitors thereof SIGNATURE THERAPEUTICS INC 2013-02-06 CN disclosed
CN-102597226-A Transaminase reactions CODEXIS INC 2012-07-18 CN disclosed
CN-102558062-A Method for synthesizing imidazole-amino acid derivative and related compound JANSSEN PHARMACEUTICA NV 2012-07-11 CN disclosed
EP-2416954-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE Global OLED Technology LLC (US) 2012-02-15 EP disclosed
CN-101514191-A Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds RIGEL PHARMACEUTICALS INC (US) 2009-08-26 CN disclosed
CN-101171012-A Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses RIGEL PHARMACEUTICALS INC (US) 2008-04-30 CN disclosed
CN-1871021-A Treating or preventing restless legs syndrome using prodrugs of GABA analogs XENOPORT INC (US) 2006-11-29 CN disclosed
CN-1839150-A Lipopeptide antibacterial derivative composition and application method thereof MIGENIX INC (CA) 2006-09-27 CN disclosed
CN-1791398-A Treating or preventing hot flashes using prodrugs of GABA analogs XENOPORT INC (US) 2006-06-21 CN disclosed
CN-1697835-A Pyridyl substituted heterocycles useful for treating or preventing HCV infection RIGEL PHARMACEUTICALS INC (US) 2005-11-16 CN disclosed
CN-1625400-A 2, 4-pyrimidinediamine compounds and uses thereof RIGEL PHARMACEUTICALS INC (US) 2005-06-08 CN disclosed
CN-1533270-A Orally administrable dosage forms of prodrugs of GABA analogs having reduced toxicity ʲŵ�������޹�˾ 2004-09-29 CN disclosed
CN-1089954-C Process for preparing carbonaceous material for negative electrode of cell and non-aqueous electrolyte secondary cell using same SONY CORP (JP) 2002-08-28 CN disclosed
CN-1138754-A Process for preparing carbonaceous material for negative electrode of cell and non-aqueous electrolyte secondary cell using same SONY CORP (JP) 1996-12-25 CN disclosed