Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.82 |
| ▸ | HPGD | P15428 | 7/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | CA12 | O43570 | 1/20 | 0.82 |
| ▸ | CA1 | P00915 | 1/20 | 0.82 |
| ▸ | CA2 | P00918 | 1/20 | 0.82 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.82 |
| ▸ | CA4 | P22748 | 1/20 | 0.82 |
| ▸ | CA6 | P23280 | 1/20 | 0.82 |
| ▸ | CA7 | P43166 | 1/20 | 0.82 |
| ▸ | CA9 | Q16790 | 1/20 | 0.82 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.82 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL28234101 | 1.00 | ALDH1A1 (0.82) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1026593 | 0.93 | ALDH1A1 (0.95) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL28520527 | 0.93 | ALDH1A1 (0.95) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL8029424 | 0.91 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29555395 | 0.91 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL27895490 | 0.91 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29362663 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1509155 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29606432 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1967 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116804825-A | Composition for forming silicon-containing metal hard mask and pattern forming method | 信越化学工业株式会社 | 2023-09-26 | — | — | CN | disclosed |
| CN-111208710-B | Iodine-containing thermosetting silicon-containing material, resist underlayer film forming composition for extreme ultraviolet lithography containing the same, and pattern forming method | 信越化学工业株式会社 | 2023-08-22 | — | — | CN | disclosed |
| CN-111458980-B | Composition for forming underlayer film of silicon-containing resist and method for forming pattern | 信越化学工业株式会社 | 2023-08-11 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-5137923-A | Lipophilic quaternary ammonium salicylates, their use in cosmetics and in dermopharmacy | L'OREAL (FR) | 1992-08-11 | — | — | US | disclosed |
| EP-0168477-B1 | USE OF A VISCO ELASTIC SURFACTANT COMPOSITION FOR CONTROLLING THE OVERALL HEAT TRANSFER COEFFICIENT OF A HEAT EXCHANGE FLUID | THE DOW CHEMICAL COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| US-4534875-A | REACTION PRODUCT OF HYDROPHOBIC HYDROPHILIC SURFACTANT AND ELECTROLYTE | THE DOW CHEMICAL COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| WO-1985003083-A1 | A METHOD FOR CONTROLLING THE OVERALL HEAT TRANSFER COEFFICIENT OF A HEAT EXCHANGE FLUID | THE DOW CHEMICAL COMPANY (US) | 1985-07-18 | — | — | WO | disclosed |
| EP-0140166-A1 | Process for reducing the drag in flowing aqueous liquids | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-08 | — | — | EP | disclosed |
| EP-0092581-A4 | FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT. | DOW CHEMICAL CO (US) | 1984-03-29 | — | — | EP | disclosed |
| EP-0092581-A1 | FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT. | DOW CHEMICAL CO (US) | 1983-11-02 | — | — | EP | disclosed |
| WO-1983001583-A1 | FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT | DOW CHEMICAL CO (US) | 1983-05-11 | — | — | WO | disclosed |