Glutarate

Glutarate

SCHEMBL5874920

CN.O=C(O)CCCC(=O)O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.79
LMNA P02545 4/20 0.67
TSHR P16473 7/20 0.62
NFKB1 P19838 2/20 0.62
PMP22 Q01453 1/20 0.62
HDAC11 Q96DB2 6/20 0.61
KMT2A Q03164 3/20 0.61
THRB P10828 2/20 0.61
BLM P54132 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
GABRR3 A8MPY1 1/20 0.61
GABRP O00591 1/20 0.61
GABRD O14764 1/20 0.61
HDAC3 O15379 1/20 0.61
GABBR2 O75899 1/20 0.61
CYP1A2 P05177 1/20 0.61
GABRA1 P14867 1/20 0.61
GABRB1 P18505 1/20 0.61
GABRG2 P18507 1/20 0.61
GABRR1 P24046 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutarate SCHEMBL27376638 1.00 SLC22A6 (0.79) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL27937715 1.00 SLC22A6 (0.79) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL5874917 1.00 SLC22A6 (0.79) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL28778929 0.93 LMNA (0.79) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL5875430 0.93 LMNA (0.79) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL5875433 0.93 LMNA (0.79) SLC22A6LMNATSHRNFKB1PMP22
Sebacic Acid SCHEMBL5874713 0.90 TSHR (0.80) SLC22A6LMNATSHRNFKB1PMP22
Azelaic Acid SCHEMBL28154518 0.90 TSHR (0.80) SLC22A6LMNATSHRNFKB1PMP22
Pimelic Acid SCHEMBL27899349 0.90 TSHR (0.80) SLC22A6LMNATSHRNFKB1PMP22
Sebacic Acid SCHEMBL27962792 0.90 TSHR (0.80) SLC22A6LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260027-A Stress sustained-release agent and preparation method and application thereof 清华大学 2022-11-01 CN claimed
CN-115260027-B Stress sustained release agent and preparation method and application thereof 清华大学 2023-08-25 CN disclosed
CN-115260027-A Stress sustained-release agent and preparation method and application thereof 清华大学 2022-11-01 CN disclosed
CN-105555292-B Method for preventing or treating diseases associated with decreased interferon receptor density 制药有限责任公司 2020-01-10 CN disclosed
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed