Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 6/20 | 0.55 |
| ▸ | GSK3A | P49840 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12895971 | 0.74 | ALDH1A1 (0.58) | CFTRGSK3AGSK3BALDH1A1LMNA | |
| SCHEMBL8985073 | 0.74 | GSK3B (0.67) | GSK3AGSK3BALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22203802 | 0.74 | SRC (0.62) | GSK3AGSK3BALDH1A1LMNARAB9A | |
| SCHEMBL14392803 | 0.74 | ALDH1A1 (0.67) | GSK3AGSK3BALDH1A1LMNARAB9A | |
| SCHEMBL12895946 | 0.73 | SRC (0.57) | GSK3AGSK3BALDH1A1LMNARAB9A | |
| SCHEMBL1729534 | 0.72 | GSK3B (0.59) | GSK3AGSK3BALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19032859 | 0.72 | CFTR (1.00) | CFTRALDH1A1LMNAMAPK1USP2 | |
| SCHEMBL29497996 | 0.72 | CFTR (1.00) | CFTRALDH1A1LMNAMAPK1USP2 | |
| SCHEMBL13259493 | 0.69 | SRC (0.57) | GSK3AGSK3BALDH1A1LMNARAB9A | |
| SCHEMBL14472561 | 0.68 | ALDH1A1 (0.50) | GSK3AGSK3BALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006511564-A | — | — | 2006-04-06 | — | — | JP | claimed |
| EP-1581477-A1 | CYCLOALKENE DICARBOXYLIC ACID COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2005-10-05 | — | — | EP | claimed |
| WO-2004056746-A1 | CYCLOALKENE DICARBOXYLIC ACID COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2004-07-08 | — | — | WO | claimed |