Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL5278800 | 1.00 | NAPRT (0.69) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL910099 | 1.00 | NAPRT (0.69) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL27638908 | 0.96 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL11080572 | 0.96 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL28167155 | 0.96 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL28075136 | 0.96 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL27941370 | 0.90 | NAPRT (0.56) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL5268186 | 0.90 | NAPRT (0.56) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Oxalic Acid SCHEMBL5874777 | 0.89 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Oxalic Acid SCHEMBL4224676 | 0.89 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119852517-A | Sodium ion battery electrolyte | 中石油深圳新能源研究院有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-118215313-A | Photovoltaic cell containing volatile solid additive and preparation method thereof | 中国科学院长春应用化学研究所 | 2024-06-18 | — | — | CN | disclosed |
| CN-111423511-B | Antigen binding proteins that bind to PD-1 | 索伦托药业有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-115093480-A | Antigen binding proteins that bind to PD-L1 | 索伦托药业有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-109467601-B | Antigen binding proteins that bind to PD-L1 | 索伦托药业有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-111423511-A | Antigen binding proteins that bind to PD-1 | 索伦托治疗有限公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-105683217-B | Antigen binding proteins that bind to PD-1 | 索伦托治疗有限公司 | 2019-12-10 | — | — | CN | disclosed |
| CN-109970561-A | The preparation method of dialkyl carbonate | 财团法人工业技术研究院 | 2019-07-05 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| CN-1064695-C | Vinyl Aromatic resin compositions containing condensation product of halogenated aromatic diol and alkylene dihalide | GEN ELECTRIC (US) | 2001-04-18 | — | — | CN | disclosed |
| CN-1137544-A | Vinyl aromatic resin compositions containing condensation product of halogenated aromatic diol and alkylene dihalide | GEN ELECTRIC (US) | 1996-12-11 | — | — | CN | disclosed |