Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4224676 | 1.00 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Oxalic Acid SCHEMBL28045246 | 0.97 | NAPRT (0.60) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Oxalic Acid SCHEMBL28045245 | 0.97 | NAPRT (0.60) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL5278800 | 0.89 | NAPRT (0.69) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL910099 | 0.89 | NAPRT (0.69) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL5875149 | 0.89 | NAPRT (0.69) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL11080572 | 0.86 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL28075136 | 0.86 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL27638908 | 0.86 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL28167155 | 0.86 | NAPRT (0.64) | NAPRTTSHRTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254535-B | Substituted pyrazolo [1,5 a] pyridine, its prepare and be used as the application of medicine | 埃斯蒂文博士实验室股份有限公司 | 2017-07-14 | — | — | CN | claimed |
| CN-1072602-A | Improve the enhanced dermal osmosis system of the local conveying of medicine | RICHARDSON VICKS INC (US) | 1993-06-02 | — | — | CN | claimed |
| CN-104387372-B | Oxo azetidine derivatives, preparation method and its purposes in human medical and cosmetics | 盖尔德马研究及发展公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-104254535-B | Substituted pyrazolo [1,5 a] pyridine, its prepare and be used as the application of medicine | 埃斯蒂文博士实验室股份有限公司 | 2017-07-14 | — | — | CN | disclosed |
| CN-101260523-A | Petroleum natural gas pipeline corrosion inhibitor prepared by waste grease and method thereof | CHENGDU DUZHIJIE SCIENCE AND T (CN) | 2008-09-10 | — | — | CN | disclosed |
| CN-101260523-A | Petroleum natural gas pipeline corrosion inhibitor prepared by waste grease and method thereof | CHENGDU DUZHIJIE SCIENCE AND T (CN) | 2008-09-10 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| CN-1087936-C | Antipsychotic method | NOVO NORDISK AS (DK) | 2002-07-24 | — | — | CN | disclosed |
| CN-1026588-C | 1-alkyl substituted benzimidazole derivatives, process for preparing same and pharmaceutical composition containing same | JANSSEN PHARMACEUTICA NV (BE) | 1994-11-16 | — | — | CN | disclosed |
| CN-1020906-C | PROCESS FOR PREPARATION OF 2-(HETEROCYCLYLALKYL) IMIDAZOPYRIDINES COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 1993-05-26 | — | — | CN | disclosed |
| CN-1030587-A | 2-(Heterocyclylalkyl) imidazopyridine | JANSSEN PHARMACEUTICA NV (BE) | 1989-01-25 | — | — | CN | disclosed |
| CN-88101286-A | 1-alkyl substituted benzimidazole derivatives, process for preparing same and pharmaceutical composition containing same | — | 1988-09-28 | — | — | CN | disclosed |