Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.85 |
| ▸ | PPARG | P37231 | 7/20 | 0.85 |
| ▸ | PPARD | Q03181 | 7/20 | 0.85 |
| ▸ | PPARA | Q07869 | 7/20 | 0.85 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.85 |
| ▸ | TSHR | P16473 | 4/20 | 0.85 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.85 |
| ▸ | FABP4 | P15090 | 3/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.85 |
| ▸ | TLR2 | O60603 | 2/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.85 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.85 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.85 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.85 |
| ▸ | MEN1 | O00255 | 1/20 | 0.85 |
| ▸ | ESR1 | P03372 | 1/20 | 0.85 |
| ▸ | PDE4A | P27815 | 1/20 | 0.85 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptanoate SCHEMBL5874770 | 1.00 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL5875259 | 1.00 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL5874655 | 1.00 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL21145133 | 1.00 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Undecanoate SCHEMBL21145311 | 1.00 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL29180306 | 1.00 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL6326052 | 1.00 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL5874261 | 1.00 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL5875188 | 0.97 | AKR1B1 (0.84) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL27850335 | 0.97 | AKR1B1 (0.84) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102533004-A | Pigment gel ink added with defoaming and foam-inhibiting agent compound step by step and preparation method thereof | UNIV EAST CHINA SCIENCE & TECH | 2012-07-04 | — | — | CN | claimed |
| EP-3873412-A1 | PERSONAL CARE COMPOSITIONS | Colgate-Palmolive Company (US) | 2021-09-08 | — | — | EP | disclosed |
| WO-2020203603-A1 | REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME | パイロットインキ株式会社 | 2020-10-08 | — | — | WO | disclosed |
| US-10723670-B2 | Blasting compositions | Dyno Nobel Asia Pacific Pty Limited (AU) | 2020-07-28 | — | — | US | disclosed |
| WO-2020117238-A1 | PERSONAL CARE COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2020-06-11 | — | — | WO | disclosed |
| US-20140311634-A1 | BLASTING COMPOSITIONS | Dyno Nobel Asia Pacific Pty Limited (AU) | 2014-10-23 | — | — | US | disclosed |
| EP-2780302-A1 | BLASTING COMPOSITIONS | Dyno Nobel Asia Pacific Pty Limited (AU) | 2014-09-24 | — | — | EP | disclosed |
| CN-103553981-A | Sodium fatty acyl oxyisopropyl sulfonate as well as synthetic method and application thereof | CHINA RES INST DAILY CHEM IND | 2014-02-05 | — | — | CN | disclosed |
| WO-2013071363-A1 | BLASTING COMPOSITIONS | DYNO NOBEL ASIA PACIFIC PTY LTD (AU) | 2013-05-23 | — | — | WO | disclosed |
| CN-1735729-B | Composition for surface treatment of substrates | GE BAYER SILICONES GMBH & CO | 2010-05-26 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| CN-1043227-C | Ceramide, preparation and application in cosmetic and dermatological pharmaceutical of same | OREAL (FR) | 1999-05-05 | — | — | CN | disclosed |
| CN-1040325-C | Application of \"changchun\" amine and its derivant for preparation of hair growing agent | DONGBEI PHARMACEUTICAL GENERAL (CN) | 1998-10-21 | — | — | CN | disclosed |
| CN-1114958-A | Application of \"changchun\" amine and its derivant for preparation of hair growing agent | DONGBEI PHARMACEUTICAL GENERAL (CN) | 1996-01-17 | — | — | CN | disclosed |
| CN-1112108-A | Ceramide, preparation and application in cosmetic and dermatological pharmaceutical of same | OREAL (FR) | 1995-11-22 | — | — | CN | disclosed |
| US-4370244-A | Process for cold mechanical working of metallic materials | AKADEMIE DER WISSENSCHAFTEN DER DDR (DD) | 1983-01-25 | — | — | US | disclosed |