SCHEMBL5875624

SCHEMBL5875624

Cc1cc(C)c(C[C@@H](N)C(=O)O)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.50
GRIA1 P42261 4/20 0.47
GRIA3 P42263 4/20 0.47
GRIA2 P42262 3/20 0.47
GRIA4 P48058 3/20 0.47
MAPT P10636 3/20 0.47
GRIK1 P39086 2/20 0.47
GRIK5 Q16478 2/20 0.47
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP2C9 P11712 2/20 0.47
KMT2A Q03164 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
TSHR P16473 1/20 0.47
CYP2C19 P33261 1/20 0.47
GRIK2 Q13002 1/20 0.47
GRIK3 Q13003 1/20 0.47
GRIK4 Q16099 1/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL287393 1.00 SLC7A5 (0.50) SLC7A5GRIA1GRIA3GRIA2GRIA4
SCHEMBL287394 1.00 SLC7A5 (0.50) SLC7A5GRIA1GRIA3GRIA2GRIA4
SCHEMBL38374 0.87 SLC7A5 (0.50) SLC7A5MAPTMEN1ALDH1A1CYP2C9
SCHEMBL10608422 0.87 SLC7A5 (0.50) SLC7A5MAPTMEN1ALDH1A1CYP2C9
SCHEMBL296690 0.87 SLC7A5 (0.50) SLC7A5MAPTMEN1ALDH1A1CYP2C9
SCHEMBL17340412 0.87 GRIA1 (0.49) SLC7A5GRIA1GRIA3GRIA2GRIA4
Hydrochloric Acid SCHEMBL10421601 0.85 SLC7A5 (0.49) SLC7A5MAPTMEN1ALDH1A1CYP2C9
Bromide SCHEMBL10477401 0.85 SLC7A5 (0.49) SLC7A5MAPTMEN1ALDH1A1CYP2C9
Bromide SCHEMBL10477399 0.85 SLC7A5 (0.49) SLC7A5MAPTMEN1ALDH1A1CYP2C9
Hydrochloric Acid SCHEMBL10477430 0.85 SLC7A5 (0.49) SLC7A5MAPTMEN1ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325469-A1 Inhibitors of atp synthase - cosmetic and therapeutic uses FORREST MICHAEL DAVID (GB) 2025-10-23 US disclosed
CN-117157049-A ATP synthase inhibitor-cosmetic and therapeutic use 迈克尔·大卫·福雷斯特 2023-12-01 CN disclosed
EP-4281034-A1 INHIBITORS OF ATP SYNTHASE - COSMETIC AND THERAPEUTIC USES Forrest, Michael, David (GB) 2023-11-29 EP disclosed
WO-2022157548-A1 INHIBITORS OF ATP SYNTHASE - COSMETIC AND THERAPEUTIC USES FORREST MICHAEL DAVID (GB) 2022-07-28 WO disclosed
US-20060155107-A1 SSTR1-selective analogs THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2006-07-13 US disclosed
US-7019109-B2 Cyclic somatostatin for use in the treatment and prevention of tumor propagation THE SALK INSTITUTE FOR BILOGICAL STUDIES (US) 2006-03-28 US disclosed
US-20020173618-A1 SSTR1-selective analogs SALK INSTITUTE OF BIOLOGICAL STUDIES, THE 2002-11-21 US disclosed
US-5750499-A ANTITUMOR THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1998-05-12 US disclosed
US-4740500-A OLIGOPEPTIDES, PROTECTED, ON RESIN SUPPORT THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1988-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325469-A1 Inhibitors of atp synthase - cosmetic and therapeutic uses ATP5F1A, ATP5F1B, ATP5ME SLC7A5 470/4885GRIA1 2295/4885GRIA3 3915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.