SCHEMBL38374

SCHEMBL38374

Cc1cc(O)cc(C)c1C[C@H](N)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.50
OPRK1 P41145 6/20 0.49
USP2 O75604 2/20 0.49
THRB P10828 2/20 0.49
RGS12 O14924 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
PKM P14618 1/20 0.49
ALOX15 P16050 1/20 0.49
NFKB1 P19838 1/20 0.49
CASP1 P29466 1/20 0.49
BRCA1 P38398 1/20 0.49
THPO P40225 1/20 0.49
CASP7 P55210 1/20 0.49
GNAI1 P63096 1/20 0.49
HIF1A Q16665 1/20 0.49
HSD17B10 Q99714 1/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296690 1.00 SLC7A5 (0.50) SLC7A5OPRK1USP2THRBRGS12
SCHEMBL10608422 1.00 SLC7A5 (0.50) SLC7A5OPRK1USP2THRBRGS12
Hydrochloric Acid SCHEMBL10421601 0.98 SLC7A5 (0.49) SLC7A5OPRK1USP2THRBRGS12
Hydrochloric Acid SCHEMBL10477430 0.98 SLC7A5 (0.49) SLC7A5OPRK1USP2THRBRGS12
Bromide SCHEMBL10477399 0.98 SLC7A5 (0.49) SLC7A5OPRK1USP2THRBRGS12
Bromide SCHEMBL10477401 0.98 SLC7A5 (0.49) SLC7A5OPRK1USP2THRBRGS12
SCHEMBL4880533 0.91 USP2 (0.49) SLC7A5OPRK1USP2THRBRGS12
SCHEMBL45405 0.91 USP2 (0.49) SLC7A5OPRK1USP2THRBRGS12
Tyrosine SCHEMBL28486531 0.89 SLC7A5 (0.71) SLC7A5OPRK1USP2THRBCYP3A4
SCHEMBL29141120 0.89 USP2 (0.46) SLC7A5OPRK1USP2THRBRGS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLE TX LTD (GB) 2025-10-23 US claimed
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2025-08-19 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
WO-2025044786-A1 PEPTIDES, DERIVATIVES THEREOF, AND USE OF SAME 南京医科大学 2025-03-06 WO claimed
US-20240382605-A1 CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2024-11-21 US claimed
US-20240350587-A1 SYSTEMS AND METHODS FOR DELIVERY OF HUMANIN OR OTHER PEPTIDES TRANSDERMAL BIOTECHNOLOGY, INC. (US) 2024-10-24 US claimed
US-20240335409-A1 SYSTEMS AND METHODS FOR DELIVERY OF PHENYLALANINE AND LACTATE TRANSDERMAL BIOTECHNOLOGY, INC. (US) 2024-10-10 US claimed
EP-4274838-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LTD (GB) 2024-09-25 EP claimed
US-12064467-B2 Systems and methods for delivery of humanin or other peptides TRANSDERMAL BIOTECHNOLOGY, INC. (US) 2024-08-20 US claimed
EP-0845003-B1 NOVEL OPIOID PEPTIDES ASTRAZENECA AB (SE) 2001-12-05 EP claimed
WO-2000043409-A2 ALPHA-CONOTOXIN PEPTIDES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2000-07-27 WO claimed
CN-1200127-A Novel opioid peptides ASTRA AB (SE) 1998-11-25 CN claimed
EP-0845003-A1 NOVEL OPIOID PEPTIDES Astra Aktiebolag (SE) 1998-06-03 EP claimed
US-5663295-A ANALGESIC, ANTIDIARRHEA BIOMEASURE INC. (US) 1997-09-02 US claimed
WO-1997007130-A1 NOVEL OPIOID PEPTIDES ASTRA AKTIEBOLAG (SE) 1997-02-27 WO claimed
EP-0644772-A4 OPIOID PEPTIDES. BIOMEASURE INC (US) 1997-01-29 EP claimed
EP-0644772-A1 OPIOID PEPTIDES BIOMEASURE, INC. (US) 1995-03-29 EP claimed
WO-1994011018-A1 OPIOID PEPTIDES BIOMEASURE, INC. (US) 1994-05-26 WO claimed
US-4273704-A N-Adamantane-substituted tetrapeptide amides G. D. SEARLE & CO. (US) 1981-06-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM SLC7A5 1166/4885OPRK1 2628/4885USP2 2161/4885
US-20240350587-A1 SYSTEMS AND METHODS FOR DELIVERY OF HUMANIN OR OTHER PEPTIDES MTPN, NLN, MFN2 SLC7A5 1045/4885OPRK1 4444/4885USP2 2489/4885
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS ACE2, SARS1, TMPRSS2 SLC7A5 2440/4885OPRK1 2039/4885USP2 2557/4885
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof GRB2, SCTR, OGFR SLC7A5 459/4885OPRK1 942/4885USP2 2537/4885
US-20240382605-A1 CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF DCLRE1B, PLK1, PAICS SLC7A5 540/4885OPRK1 3025/4885USP2 4789/4885
US-12064467-B2 Systems and methods for delivery of humanin or other peptides MTPN, NLN, MFN2 SLC7A5 1045/4885OPRK1 4444/4885USP2 2489/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT SLC7A5 64/4885OPRK1 2051/4885USP2 1460/4885
US-20240335409-A1 SYSTEMS AND METHODS FOR DELIVERY OF PHENYLALANINE AND LACTATE TYR, LANCL2, LRAT SLC7A5 268/4885OPRK1 2866/4885USP2 1470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.