SCHEMBL5875758

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16992953	1.00	NPC1 (0.64)	NPC1RAB9ACSNK1DATAD2SMN1; SMN2
	SCHEMBL5875681	0.89	PSEN1 (0.58)	NPC1RAB9ACSNK1DSMN1; SMN2MEN1
	SCHEMBL5875689	0.88	PSEN1 (0.55)	CSNK1DDYRK1APSEN1PSEN2APH1B
	SCHEMBL8260317	0.80	KMT2A (0.63)	NPC1RAB9ASMN1; SMN2TSHRMEN1
	SCHEMBL5875524	0.80	KMT2A (0.63)	NPC1RAB9ASMN1; SMN2TSHRMEN1
	SCHEMBL5875506	0.79	PSEN1 (0.69)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL5875772	0.77	PSEN1 (0.54)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL17287785	0.77	CSNK1D (1.00)	NPC1RAB9ACSNK1DSMN1; SMN2TSHR
	SCHEMBL5875822	0.77	PSEN1 (0.56)	MEN1KMT2AALDH1A1PSEN1PSEN2
	SCHEMBL3099320	0.76	PSEN1 (0.58)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.