Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5877457 | 1.00 | KMT2A (0.39) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3135126 | 0.79 | KMT2A (0.44) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3135120 | 0.79 | KMT2A (0.44) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL31590369 | 0.79 | KMT2A (0.44) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5870467 | 0.79 | KMT2A (0.44) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL8563627 | 0.70 | BACE1 (0.41) | KMT2ABACE1 | |
| SCHEMBL8563625 | 0.70 | BACE1 (0.41) | KMT2ABACE1 | |
| SCHEMBL8563622 | 0.70 | BACE1 (0.41) | KMT2ABACE1 | |
| SCHEMBL20924918 | 0.69 | TSHR (0.39) | KMT2ACHRNB2CHRNA4BACE1 | |
| SCHEMBL16752661 | 0.68 | FFAR3 (0.38) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115705-B2 | Method of producing a polythiourethane and method of producing a graft polymer | JSR CORPORATION (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20050250926-A1 | Method of producing a polythiourethane and method of producing a graft polymer | JSR CORPORATION (JP) | 2005-11-10 | — | — | US | disclosed |